The Lead Episode 142: A Discussion of Class 1c Antiarrhythmic Therapy Following PCI in New Onset Atrial Fibrillation: Safety and Clinical Outcomes from a Nationwide Cohort

About this episode

The episode discusses the safety and clinical outcomes of Class 1c antiarrhythmic therapy following PCI in patients with new-onset atrial fibrillation.

Join an expert-led discussion exploring the safety and clinical outcomes of Class 1c antiarrhythmic therapy following percutaneous coronary intervention (PCI) in patients with new-onset atrial fibrillation, based on insights from a nationwide cohort study. Deep Chandh Raja, MBBS, MD, PhD (Australian National University and Kauvery Hospital) hosts a dynamic conversation with Sandeep Gautam, MD, MPH, FHRS (University of Missouri Health) and Deepak Padmanabhan, MD, FHRS (Narayana Institute of Cardiac Sciences, Bengaluru). Together, they examine real-world data on the use of Class 1c agents in a traditionally high-risk population, addressing long-standing concerns about proarrhythmia and ischemic heart disease. The discussion will highlight patient selection, evolving clinical practice patterns, and implications for guideline-directed management, offering clinicians practical insights into optimizing rhythm control strategies in complex post-PCI patients. Learning Objectives Evaluate the safety profile and clinical outcomes associated with Class 1c antiarrhythmic therapy in patients with new-onset atrial fibrillation following PCI. Identify appropriate patient selection criteria and…

People in this episode

Host: Deep Chandh Raja, MBBS, MD, PhD

Guests: Sandeep Gautam, MD, MPH, FHRS, Deepak Padmanabhan, MD, FHRS

Topics covered

• Class 1c antiarrhythmic therapy
• new-onset atrial fibrillation
• percutaneous coronary intervention
• safety and clinical outcomes
• patient selection
• guideline-directed management

Keywords

• antiarrhythmic therapy
• atrial fibrillation
• PCI
• proarrhythmia
• ischemic heart disease
• clinical outcomes
• patient selection

Mentioned in this episode

Organizations: Australian National University, Kauvery Hospital, University of Missouri Health, Narayana Institute of Cardiac Sciences, Bengaluru

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