Understanding Female Metabolism: PCOS, Postpartum, and Menopause | Madison Kackley, PhD | The Metabolic Link

Understanding Female Metabolism: PCOS, Postpartum, and Menopause | Madison Kackley, PhD | The Metabolic Link

April 21, 2026 · 1h 24m · Episode 93

About this episode

The episode discusses the impact of ketogenic interventions on female metabolism, particularly in relation to PCOS, postpartum recovery, and menopause.

In a 12-week clinical trial at The Ohio State University, every woman with PCOS who completed the intervention experienced a change in her menstrual status. One participant, who had never had a period in her life, began menstruating within a week. Another saw spotting after five years of amenorrhea while taking only a ketone supplement without adopting a ketogenic diet. These are among the earliest controlled findings linking ketogenic interventions directly to reproductive hormone restoratio...

People in this episode

Hosts: Dr. Dominic D'Agostino, Dr. Angela Poff, Victoria Field

Guest: Madison Kackley, PhD

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Organizations: The Ohio State University

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