Progesterone Intolerance: Why Progesterone Side Effects Can Make You Feel Worse on HRT
About this episode
This episode discusses progesterone intolerance and its side effects in women undergoing hormone replacement therapy.
➡️ Get the 30 Gram Midlife Breakfast Cheat Sheet If progesterone is supposed to help you sleep, calm your nervous system, and balance your hormones… why can it make some women feel absolutely terrible? In this episode of The Midlife Realignment, I’m breaking down progesterone intolerance —one of the most frustrating and misunderstood problems I see in women using hormone replacement therapy (HRT). If you’ve experienced progesterone side effects like extreme grogginess, depression, anxiety, brain fog, bloating, constipation, diarrhea, or the feeling that you’ve been hit by a truck after taking oral progesterone, there may be a biological reason. I explain how oral progesterone is metabolized into the neurosteroid allopregnanolone, how it interacts with GABA receptors in the brain, and why two women can take the exact same progesterone dose and have completely opposite reactions. I also break down why 100 mg of progesterone may be far too much for one woman—and potentially not enough for another. 🔥 In this episode, you’ll learn: What progesterone intolerance is and the symptoms to watch for Why progesterone can cause anxiety, depression, grogginess, and GI symptoms How…
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