This Rare Condition Causes Extreme, Insatiable Hunger

This Rare Condition Causes Extreme, Insatiable Hunger

August 10, 2026 · 44 min · Episode 911

About this episode

The episode discusses the Rao family's experience with their daughter Ayoni's diagnosis of Prader-Willi Syndrome, a condition that causes extreme hunger.

The Rao family in Maryland knew that something was different about their younger daughter, Ayoni, almost as soon as she was born. But it took them until she was five to get a diagnosis of Prader-Willi Syndrome, a rare genetic condition that causes extreme, insatiable hunger. Food needs to be locked away from many of these patients, or they might eat until their stomachs actually rupture.

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