630. How to FIX Your Gut to Fix Your Hormones

630. How to FIX Your Gut to Fix Your Hormones

May 15, 2026 · 50 min

About this episode

Dr. Amie Hornaman interviews Dr. Cassie Smith about the connection between gut health and hormone balance.

In this episode, I sit down with board certified endocrinologist Dr. Cassie Smith to unpack the powerful connection between your gut, hormones, metabolism, and overall health. We dive into why so many people are still struggling despite “normal labs,” why conventional medicine continues to miss key thyroid markers, and how gut dysfunction can quietly sabotage everything from T3 conversion to estrogen metabolism. Dr. Cassie shares her own story of being medically gaslit, dismissed, and forced to search for answers after Graves’ disease turned her life upside down, and how that journey completely transformed the way she practices medicine today. We talk about reverse T3, leaky gut, autoimmune disease, estrogen dominance, cancer risk, thyroid medication misconceptions, and the frustrating “eat less, exercise more” advice that continues to fail women every day. Dr. Cassie also shares practical free strategies anyone can start implementing immediately to support healing and finally feel better. What you’ll learn: Why “normal labs” might still leave you feeling completely hypothyroid The surprising role gut bacteria play in thyroid hormone conversion What actually happens when T3…

People in this episode

Host: Dr. Amie Hornaman

Guest: Dr. Cassie Smith

Topics covered

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