Apr 10 2026 This Week in Cardiology

Apr 10 2026 This Week in Cardiology

From This Week in Cardiology by Medscape

April 10, 2026 · 32 min

About this episode

John Mandrola, MD, discusses recent trials related to imaging-guided PCI, LDL targets, and beta-blocker withdrawals.

Three imaging-guided PCI trials (two with surprising results), LDL targets, an oral PCSK9 inhibitor, and another beta-blocker withdrawal trial are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only . To read a partial transcript or to comment, visit: https://www.medscape.com/twic I IVUS-Guided PCI OPTIMAL Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2600440 IVUS-CHIP Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2601521 ILUMIEN IV Trial https://www.nejm.org/doi/10.1056/NEJMoa2305861 DKCRUSH VIII Trial https://doi.org/10.1016/j.jacc.2026.01.081 II Ez-PAVE Trial — Low vs Very Low LDL-targets Does Ez-PAVE Support 'Lower Is Better' for LDL-C? https://www.medscape.com/viewarticle/does-ez-pave-support-lower-better-ldl-c-2026a1000akx Ez-PAVE Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2600283 2026 ACC/AHA Lipid Guidelines https://www.ahajournals.org/doi/10.1161/CIR.0000000000001423 III CORALreef AddOn CORALreef AddOn Trial https://www.jacc.org/doi/abs/10.1016/j.jacc.2026.03.036 This Week in Caardiology 2-6-26 https://www.medscape.com/viewarticle/1003240 CORALreef Lipids Trial…

People in this episode

Host: John Mandrola, MD

Topics covered

  • imaging-guided PCI trials
  • LDL targets
  • oral PCSK9 inhibitor
  • beta-blocker withdrawal trials

Keywords

  • PCI trials
  • LDL targets
  • PCSK9 inhibitor
  • beta-blocker withdrawal
  • healthcare professionals

Mentioned in this episode

Organizations: Medscape, NEJM, ACC, AHA

More episodes of This Week in Cardiology

Explore listener stats, chart rankings, contacts and more on the This Week in Cardiology podcast page.