Apr 17 2026 This Week in Cardiology

Apr 17 2026 This Week in Cardiology

From This Week in Cardiology by Medscape

April 17, 2026 · 28 min

About this episode

This episode discusses various clinical trials and studies related to heart failure and peripheral artery disease.

SPIRIT-HF, another spironolactone trial in HFpEF; the ESSENCE imaging study of the drug olezarsen; the SirPAD trial in peripheral artery disease; and ultrasound-guided femoral venous access are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only . To read a partial transcript or to comment, visit: https://www.medscape.com/twic I ACC: SPIRIT-HF Trial FINEARTS-HF Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2407107 TOPCAT Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1313731 TOPCAT Americas Trial https://www.ahajournals.org/doi/10.1161/circulationaha.114.013255 II A New Class of Lipid Lowering Drug Has a Dubious Debut At ACC ESSENCE-TIMI 73b Imaging Study https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.126.080012 ESSENCE-TIMI 73b Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2507227 IMPROVE IT Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1410489 III Drug-Coated Balloons Looked Quite Good in PAD interventions Sirolimus-Coated Balloon Reduces Amputation Risk in Peripheral Artery Disease…

People in this episode

Host: John Mandrola, MD

Topics covered

  • heart failure
  • imaging study
  • peripheral artery disease
  • ultrasound-guided access
  • clinical trials

Keywords

  • SPIRIT-HF
  • ESSENCE
  • SirPAD
  • spironolactone
  • olezarsen
  • sirolimus-coated balloon
  • clinical trials

Mentioned in this episode

Organizations: SPIRIT-HF, ESSENCE, SirPAD, European Heart Rhythm Association, Medscape

Products: spironolactone, olezarsen, sirolimus-coated balloon

More episodes of This Week in Cardiology

Explore listener stats, chart rankings, contacts and more on the This Week in Cardiology podcast page.