May 22 2026 This Week in Cardiology

May 22 2026 This Week in Cardiology

From This Week in Cardiology by Medscape

May 22, 2026 · 32 min

About this episode

John Mandrola, MD discusses recent developments in cardiology including digoxin trials, a new GLP-1 drug, vagal nerve stimulation, and updates on lipid guidelines.

Three more digoxin trials, yet another GLP-1 drug on the horizon, vagal nerve stimulation, trial inside baseball, and more on lipid guidelines are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only . To read a partial transcript or to comment, visit: https://www.medscape.com/twic I More About Low-dose Digoxin in HF — The DECISION Trial(s) DECISION Trial https://www.nature.com/articles/s41591-026-04406-6 Digitalis Glycosides in HF — JAMA Meta-Analysis https://jamanetwork.com/journals/jama/fullarticle/2848972 DIGIT-HF Trial https://www.nejm.org/doi/10.1056/NEJMoa2415471 RADIANCE Trial (1993) https://www.nejm.org/doi/full/10.1056/NEJM199307013290101 DECISION Withdrawal Study https://doi.org/10.1093/eurheartj/ehag385 Digoxin Discontinuation vs Continuation in Chronic HF https://doi.org/10.1016/j.amjcard.2007.02.099 II Yet another GLP-1 Drug Announced this Week Lillly News Release on Retatrutide https://investor.lilly.com/news-releases/news-release-details/lillys-triple-agonist-retatrutide-delivered-powerful-weight-loss III A Big Story in HF Science – Vagal Nerve Stimulation in HFrEF ANTHEM HFrEF trial…

People in this episode

Host: John Mandrola, MD

Topics covered

Mentioned in this episode

Organizations: Medscape

Products: digoxin, GLP-1 drug

Books & works: Lipid Guidelines

More episodes of This Week in Cardiology

Explore listener stats, chart rankings, contacts and more on the This Week in Cardiology podcast page.