
346: Metabolism and Porin Permeability
From This Week in Microbiology by Vincent Racaniello
December 13, 2025 · 54 min · Episode 346
About this episode
The episode discusses how nutrient competition affects drug side effects on gut microbiota and the role of metabolic control in porin permeability and antibiotic resistance.
TWiM explains how competition for nutrients anticipates and potentially mitigate drug side effects on the gut microbiota, and metabolic control of porin permeability influences antibiotic resistance. Hosts: Vincent Racaniello , Michael Schmidt and Petra Levin Guest: Mark O. Martin Become a patron of TWiM. Links for this episode: Nutrient competition predicts drug effects on microbiota (Cell) Metabolic control of porin permeability influences antibiotic resistance in E coli (Nat Micro) Santiago Cano-Muniz Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv
People in this episode
Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin
Guest: Mark O. Martin
Topics covered
- metabolism
- porin permeability
- antibiotic resistance
- gut microbiota
- nutrient competition
Keywords
- metabolism
- porin permeability
- antibiotic resistance
- gut microbiota
- nutrient competition
Mentioned in this episode
Organizations: Cell, Nat Micro
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