Why Your Company Should Own Its AI Model | E2278

Why Your Company Should Own Its AI Model | E2278

From This Week in Startups by Jason Calacanis

April 21, 2026 · 1h 17m

About this episode

The episode discusses the importance of companies owning their AI models and features insights from industry leaders.

This Week In Startups is made possible by: Quo - https://quo.com/TWiST Vanta - https://vanta.com/twist Pilot - https://pilot.com/twist Plaud - https://Plaud.ai/twist Today’s show: *Eragon CEO Josh Sirota believes that you should “own your intelligence.” He demos a live enterprise AI operating system connecting email, Slack, calendar, and financial data into a single agentic layer that’s pre-trained to understand any business inside and out. PLUS we’ve got IONA Drones founder Etienne Louvet, a first look at Moonshot’s Kimi K2.6, and a brand new Off Duty with JCal and Lon. FULL SHOW NOTES ON NOTION: https://thisweekinstartups-docket.notion.site/TWiST-2278-SHOW-NOTES-34872ca918e380bd9c71e684ce2db7c9?source=copy_link Guests : Eragon: https://eragon.ai Josh Sirota on X: https://x.com/joshua_sirota IONA: https://ionadrones.com/ Etienne Louvet on X: https://x.com/etienneldva Relevant Links Eragon Seed Round coverage: https://techcrunch.com/2026/03/18/this-startup-wants-to-make-enterprise-software-look-more-like-a-prompt/ Neurometric: https://www.neurometric.ai/ Ollama model: https://ollama.com/ Orange Slice: https://www.orangeslice.ai/ Corgi Insurance: https://www.corgi.insure/ Slash…

People in this episode

Host: Jason Calacanis

Guests: Josh Sirota, Etienne Louvet

Topics covered

  • AI ownership
  • enterprise software
  • technology integration
  • startups
  • drones

Keywords

  • AI model
  • enterprise AI
  • technology
  • startups
  • drones
  • Josh Sirota
  • Etienne Louvet

Sponsors

Quo, Vanta, Pilot, Plaud

Mentioned in this episode

Organizations: Eragon, IONA Drones, Moonshot

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