
Lung Organoids, Autism and Sarcopenia Insights in Mice, and a Bidding War Ends
From Touching Base by Genetic Engineering & Biotechnology News (GEN)
December 4, 2025 · 36 min · Episode 40
About this episode
The episode discusses recent breakthroughs in lung organoids and autism research, along with business news regarding a bidding war in the pharmaceutical industry.
Stories on lung organoids and autism were some of the most read this week. We kicked things off by digging into recent breakthroughs in both areas including an automated method for manufacturing iPSC-derived lung organoids and how a combination of supplements reduced autism-linked behaviors in mice. Still on the topic of new research, we discussed how a protein in the extracellular matrix helps muscle stem cells repair aging muscles. In business news, the bidding war between Lundbeck and Alkermes over Avadel Pharmaceuticals has ended. We talk about the possible implications of Lundbeck’s decision to back out and next steps for Alkermes. Then we dive into Protego Biopharma’s recent fundraising round, and efforts to develop small-molecule pharmacological chaperones that modulate protein stability in disease. Join GEN editors Corinna Singleman, PhD, Alex Philippidis, and Uduak Thomas for a discussion of the latest biotech and biopharma news. Listed below are links to the GEN stories referenced in this episode of Touching Base : Lung Organoids Generated in Bulk Using Stirred Bioreactor Technology GEN , December 1, 2025 Autism-Linked Behaviors…
People in this episode
Hosts: Corinna Singleman, Alex Philippidis, Uduak Thomas
Topics covered
- lung organoids
- autism
- sarcopenia
- biotech news
- biopharma
- bidding war
Keywords
- lung organoids
- autism
- sarcopenia
- biotech
- biopharma
- bidding war
- research breakthroughs
Mentioned in this episode
Organizations: Lundbeck, Alkermes, Avadel Pharmaceuticals, Protego Biopharma, GEN
Products: iPSC-derived lung organoids, small-molecule pharmacological chaperones
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