How Understanding Your Brain Chemistry Can Change Your Life

How Understanding Your Brain Chemistry Can Change Your Life

From Weirdly Helpful (formerly The Best Advice Show) by Zak Rosen

April 22, 2026 · 20 min

About this episode

Mike Pesca discusses how understanding neurochemistry can provide new insights into mental health and anxiety.

Mike Pesca is the creator and host of The Gist, the longest-running daily news podcast in history, moderator of Not Even Mad, a political debate podcast, and host of Funny You Should Mention, a co-production with the Comedy Cellar, where he conducts in-depth interviews with stand up comedians. On today's show we get into how understanding your own neurochemistry can offer new perspectives on mental health and anxiety. READ: Opinion | The Feel-Good Gene LISTEN: How to address acute anxiety with Terry Rawls --- LISTEN: You in Mind |Yoni London --- LISTEN TO WH ad-free by becoming a Patron today! WH MERCH IS HERE!!!!!!!! Learn more about your ad choices. Visit megaphone.fm/adchoices

People in this episode

Host: Zak Rosen

Guest: Mike Pesca

Topics covered

  • brain chemistry
  • mental health
  • anxiety
  • neurochemistry
  • podcast
  • interviews

Keywords

  • brain chemistry
  • mental health
  • anxiety
  • neurochemistry
  • podcast
  • Mike Pesca

Mentioned in this episode

Organizations: The Gist, Not Even Mad, Funny You Should Mention, Comedy Cellar

Books & works: The Feel-Good Gene

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