Doctors Reveal the EARLY Signs of Alzheimer’s (Before Memory Loss) With Dr. Melissa Murray

Doctors Reveal the EARLY Signs of Alzheimer’s (Before Memory Loss) With Dr. Melissa Murray

From Alzheimer’s Breakthrough with Dr. Josh Helman, MD by Dr. Josh Helman, MD

March 26, 2026 · 1h 4m · Episode 62

About this episode

Dr. Melissa Murray discusses the early signs of Alzheimer's and the importance of treating it as a family of diseases.

What if Alzheimer’s isn’t just one disease but a family of diseases? In this episode, I’m thrilled to be joined by Dr. Melissa Murray, a professor of neuroscience at the Mayo Clinic. Dr. Murray’s groundbreaking research focuses on Alzheimer’s, dementia with Lewy bodies, and other neurodegenerative conditions. She leads the Mayo Clinic’s Translational Neuropathology Lab, where her team combines neuropathology, neuroimaging, and genetics to understand these diseases better. Dr. Murray is one of the recent winners of the Rainwater Prize for Outstanding Innovation in Neurodegenerative Research, which came with a $400,000 prize to further her and her colleague Dr. Dennis Dickson's research at Mayo Clinic. The Rainwater Prize honors scientific contributions to the field of neurodegenerative research that focus on diseases associated with the accumulation of tau protein in the brain, with the goal of translating discoveries into meaningful therapeutic and diagnostic innovations. Today’s discussion tackles a critical issue in brain health: treating Alzheimer’s like it’s a single disease. With advances in neuroimaging and biomarkers, we can now diagnose Alzheimer’s while people are still…

People in this episode

Host: Dr. Josh Helman

Guest: Dr. Melissa Murray

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Organizations: Mayo Clinic, Translational Neuropathology Lab, Rainwater Prize

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