393: Alzheimer's Starts Decades Before Symptoms…Here's Why | David Perlmutter

393: Alzheimer's Starts Decades Before Symptoms…Here's Why | David Perlmutter

July 15, 2026 · 1h 16m

About this episode

Dr. David Perlmutter discusses the science behind Alzheimer's disease and its prevention.

Neurologist and bestselling author Dr. David Perlmutter returns to discuss the groundbreaking science behind his new book, Brain Defenders. Together, we unpack why Alzheimer's disease may be driven less by amyloid plaques and more by chronic inflammation, metabolic dysfunction, and changes in the brain's immune cells. Dr. Perlmutter explains the critical role of microglia, how blood sugar and insulin resistance affect the brain, why gut health is directly connected to cognitive function, and what lifestyle habits have the strongest evidence for protecting memory as we age. → Leave Us A Voice Message!  Topics Discussed: → What causes Alzheimer's disease? → How do you prevent Alzheimer'? → What foods improve brain health? → Can inflammation cause dementia? → Does blood sugar affect memory? Sponsored By:  → Function | Check your health the way I do. Function provides 160+ lab tests for $1/day and member pricing on advanced imaging. Join at https://functionhealth.com/bewellbykelly and use code BEWELL25 for a $25 credit. → Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at https://bewellbykelly.com. → Shop minnow's new apré-ski capsule…

People in this episode

Host: Kelly Leveque

Guest: David Perlmutter

Topics covered

Keywords

Sponsors

Function, Be Well By Kelly Protein Powder & Essentials, minnow, LMNT

Mentioned in this episode

Books & works: Brain Defenders

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