Feeling Stuck on Antidepressants in Midlife? How to Taper Off Safely with Mark Horowitz, PhD

Feeling Stuck on Antidepressants in Midlife? How to Taper Off Safely with Mark Horowitz, PhD

March 23, 2026 · 1h 26m

About this episode

Dr. Mark Horowitz discusses the long-term effects of antidepressants and how to taper off safely.

56 million Americans are on antidepressants — and 25 million have been for more than five years. Psychiatry researcher and de-prescribing expert Dr. Mark Horowitz unpacks what antidepressants are actually doing to your brain and body over the long term, including effects on mood, weight, sleep, memory, and sexual function. Watch the full episode at https://youtu.be/30Y9eMEqltA

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