Review Series on Clonal Tracking in Hematopoiesis
About this episode
This episode features interviews with authors discussing clonal tracking in hematopoiesis and its implications in cancer research.
In this Review series episode, Blood associate editor Dr. Diane Krause interviews contributing authors from the Review Series on Clonal tracking in Hematopoiesis published in volume 147 issue 23 of Blood . Dr. Alejo E. Rodriguez-Fraticelli speaks to the development of his paper, " Clonal tracing of blood stem cells across mouse and human lifespans ”, which provides a detailed overview of the experimental approaches that make clonal analysis possible, and which approaches are most appropriate to use to address specific questions. Dr. Shalin H. Naik speaks about how different clonal tracking approaches have been used to address the central question of clonal fate specification of stem and progenitor cells to specific lineages in “ The evolution of hematopoietic models through a clonal lens ”. Finally, Dr. Federico Gaiti speaks about “ Methylation-based lineage tracing in cancer ”, which takes these ideas into the context of cancer, focusing on how DNA methylation can be used to reconstruct clonal relationships.
People in this episode
Host: Dr. Diane Krause
Guests: Dr. Alejo E. Rodriguez-Fraticelli, Dr. Shalin H. Naik, Dr. Federico Gaiti
Mentioned in this episode
Organizations: Blood
Books & works: Clonal tracing of blood stem cells across mouse and human lifespans, The evolution of hematopoietic models through a clonal lens, Methylation-based lineage tracing in cancer
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