Oral GLP-1 (Wegovy) Is Here: Dosing, Switching, and What to Expect

Oral GLP-1 (Wegovy) Is Here: Dosing, Switching, and What to Expect

From Docs Who Lift by Docs Who Lift

January 20, 2026 · 25 min · Episode 141

About this episode

Spencer and Dr. Karl discuss the introduction of oral GLP-1 Wegovy, its dosing, switching from injections, and insights from SURMOUNT 4 data.

Oral GLP 1 Wegovy is finally here, so Spencer and Dr. Karl break down how it actually works, how to dose it, and how they are switching people from injections like Wegovy and Zepbound in real clinic settings. They also walk through new SURMOUNT 4 data on what happens when people stop tirzepatide, including who maintains, who regains, and why a personalized plan matters.

People in this episode

Host: Spencer

Guest: Dr. Karl

Topics covered

  • GLP-1
  • Wegovy
  • dosing
  • switching medications
  • SURMOUNT 4 data
  • personalized plans

Keywords

  • Wegovy
  • GLP-1
  • dosing
  • tirzepatide
  • SURMOUNT 4
  • weight loss
  • medication switching

Mentioned in this episode

Products: Wegovy, Zepbound, tirzepatide

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