Ep. 586 The Estrogen Masterclass: The Truth About HRT, Heart Health & Hair Loss | Menopause, Perimenopause & HRT

Ep. 586 The Estrogen Masterclass: The Truth About HRT, Heart Health & Hair Loss | Menopause, Perimenopause & HRT

From Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+ by Everyday Wellness™

April 29, 2026 · 54 min

About this episode

This episode features a mashup of expert insights on the role of estrogen in women's health during midlife, focusing on its impact on brain health and various physiological changes during menopause.

We have an estrogen masterclass mashup episode today, featuring Dr. Carrie Jones, Dr. Stephanie Estima, Dr. Sarah Berry, Dr. Thomas Dayspring, and Dr. Kellyann Niotis, who share their insights on estrogen and women’s health in midlife. In this mashup masterclass, we’re bringing together a powerful compilation of conversations centered on the impact of hormones on brain health and cognition. We explore the nuanced risk factors for neurocognitive changes and how shifts in insulin sensitivity during perimenopause and menopause influence various aspects, including lipid patterns, hair changes, laboratory markers, and lifestyle inputs. We examine how the gut microbiome changes dynamically, targeted nutritional interventions, the role of advanced testing, including the DUTCH test, and how genetics, detoxification pathways, methylation, and the estrobolome. This is an exciting, dynamic mashup of some of my favorite podcast conversations dedicated to estrogen and midlife physiology. It’s one you’ll likely want to revisit more than once. IN THIS EPISODE, YOU WILL LEARN: The critical role estrogen plays neurologically, and how estrogen receptors in the brain increase as estrogen declines…

People in this episode

Guests: Dr. Carrie Jones, Dr. Stephanie Estima, Dr. Sarah Berry, Dr. Thomas Dayspring, Dr. Kellyann Niotis

Topics covered

  • estrogen
  • menopause
  • perimenopause
  • hormones
  • brain health
  • gut microbiome
  • insulin sensitivity

Keywords

  • HRT
  • heart health
  • hair loss
  • lipid metabolism
  • neurocognitive changes
  • DUTCH test
  • methylation

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