
LEAN: Resetting Metabolism and Appetite Naturally
From Healthful Pursuit Podcast by Leanne Vogel
February 24, 2026 · 57 min · Episode 566
About this episode
This episode discusses the LEAN peptide and its role in resetting metabolism and appetite naturally.
Weight gain isn't a willpower problem… It's a communication problem. In this episode, we explore LEAN, the peptide that helps the body re-establish normal metabolic signaling between the gut, brain, and fat cells. You'll learn how this yeast-derived peptide extends your own GLP-1 activity, balances appetite hormones, and supports fat oxidation using citrus polyphenols, L-carnitine, and CoQ10, all without stimulants or artificial suppression. We'll cover how LEAN works, what to expect in the first few weeks and months, and why pairing it with FIT helps preserve muscle and keep metabolism strong. Hosted by Leanne Vogel. Coaching with Leanne: https://www.healthfulpursuit.com/coaching Bioactive Peptides: https://www.healthfulpursuit.com/make Quiz - your personalized peptide stack: https://www.healthfulpursuit.com/quiz Enjoy today's show. Thanks for listening!
People in this episode
Host: Leanne Vogel
Topics covered
- metabolism
- appetite regulation
- peptides
- nutrition
- weight management
Keywords
- metabolic signaling
- appetite hormones
- fat oxidation
- yeast-derived peptide
- natural supplements
Mentioned in this episode
Products: LEAN, GLP-1, L-carnitine, CoQ10, citrus polyphenols
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