Ep. 142  GLP-1 and Perimenopause: Why It Works Differently in a Midlife Body

Ep. 142 GLP-1 and Perimenopause: Why It Works Differently in a Midlife Body

May 24, 2026 · 12 min · Episode 142

About this episode

This episode discusses how GLP-1 works differently in perimenopausal and menopausal women and the implications for their weight loss results.

You're on a GLP-1 and following the advice. But the advice wasn't built for a perimenopausal body. In this episode I break down exactly why GLP-1 works differently in perimenopause and menopause — and what that means for your results. Perfect for women in perimenopause or menopause who are on a GLP-1 and wondering why their experience doesn't match what they expected. 00:00 Show Intro 01:09 GLP-1 In Midlife 01:39 Two Women Two Outcomes 02:15 Why Protocols Miss Women 03:17 Quick Quiz Break 04:05 Insulin Sensitivity Shift 05:06 Muscle Loss Risk 06:33 Cortisol Stress Factor 07:53 Hunger Signals Unreliable 08:34 What To Do Instead 10:10 Program Invitation 11:29 Wrap Up And Goodbye Check out the full show notes at https://cindistickle.com/podcast/ep-142-glp-1-and-perimenopause-why-it-works-differently-in-a-midlife-body Connect with Cindi Perimenopause Morning Reset — https://cindistickle.myflodesk.com/nervoussystemorningresetpodcast Book a Metabolism Consultation — https://cal.com/cindi-stickle/metabolism-consultation Come hang out in my Facebook Group — https://www.facebook.com/groups/nobsmenopause

People in this episode

Host: Cindi Stickle

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Mentioned in this episode

Products: GLP-1

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