
From Clinician to Chief Health AI Officer: A Conversation with Dr. Karandeep Singh
From NEJM AI Grand Rounds by NEJM Group
September 17, 2025 · 1h 3m · Episode 34
About this episode
Dr. Karandeep Singh discusses the intersection of programming and medicine, focusing on health AI and its implications for patient care.
Dr. Karandeep Singh brings two worlds together: programming and medicine. In this conversation, he explains how early experiments with code led him to biomedical informatics, why gaps between paper performance and clinical reality must be confronted, and how governance committees weigh ethics and safety. Now serving as Chief Health AI Officer at UC San Diego Health, he reflects on lessons from deploying sepsis prediction tools, the risks of hype, and the promise of integration. For clinicians, Singh’s story is a reminder that the best AI is guided by patient care, deep expertise, and humility about the limits of technology. Transcript.
People in this episode
Guest: Dr. Karandeep Singh
Topics covered
- health AI
- biomedical informatics
- clinical governance
- sepsis prediction
- ethics in AI
Keywords
- health AI
- biomedical informatics
- sepsis prediction
- clinical reality
- ethics
- technology limits
Mentioned in this episode
Organizations: UC San Diego Health
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