185 The Science of Ozempic and What Happens After You Stop | Dr Tom Buckley

185 The Science of Ozempic and What Happens After You Stop | Dr Tom Buckley

From Performance Intelligence by Andrew May

June 17, 2026 · 1h 0m

About this episode

Dr. Tom Buckley discusses the science behind Ozempic and its effects on hunger and weight loss.

Inside the venom of a desert lizard, scientists found a molecule that does something the diet industry spent 50 years failing to do. It quietly switches off hunger. That molecule is now the most talked about drug on the planet, and it's sitting in the fridges of millions of people who couldn't explain how it works if you paid them. Dr Tom Buckley, 30 years in medicine and a professor at Sydney University, has looked at the evidence and called these drugs revolutionary . But what about "Ozempic face"? What if the wait comes back after you stop? Who should never touch these drugs? Dr Tom and Andrew get into the science so you finally have all the answers you need. 00:00 – A desert lizard that eats twice a year 03:32 – What a GLP-1 actually is, in plain English 07:36 – Ghrelin and leptin: hunger and fullness, explained 10:23 – The venom that cracked the hunger code 14:06 – Why your body is built to hold onto fat 15:19 – How to raise GLP-1 without a prescription 18:10 – Become the CEO of your body and brain 22:10 – You don't lose fat cells, they shrink 24:39 – "Ozempic face," and why you lose weight slowly 28:17 – The "Limitless" effect: cognitive horsepower 29:28 – 76 trials, 40,000…

People in this episode

Host: Andrew May

Guest: Dr Tom Buckley

Topics covered

Keywords

Mentioned in this episode

Organizations: Sydney University

Products: Ozempic

Places: desert

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