About this episode

Dr. Autumn Smith interviews Dr. Mark Hyman about the real reasons behind stubborn weight gain and the impact of ultra-processed foods on health.

IN THIS EPISODE We've been told weight loss is simple: "Eat less and move more." And if you can't… it must be a willpower problem. But Dr. Mark Hyman says this story doesn't match what we're seeing in real life… or what the science actually shows. In this episode of the ReThink Health Podcast, I sit down with Dr. Hyman to unpack the real drivers behind stubborn weight gain (and why so many people feel like their body is working against them). We talk about how today's food environment is built around ultra-processed, hyper-palatable ingredients that don't just add calories; they change your biology, disrupt appetite signals, and push the body toward insulin resistance and fat storage. You'll also hear Dr. Hyman's grounded take on the "fat vs. carbs" debate, why food quality matters more than diet labels, and what simple shifts actually move the needle — without shame, extremes, or perfectionism. You'll learn: Why "calories in, calories out" doesn't explain stubborn weight gain How ultra-processed foods can hijack hunger, energy, and cravings The #1 dietary driver behind metabolic dysfunction (and why bread isn't "better" than sugar) Why vilifying fat backfired — and what matters…

People in this episode

Host: Dr. Autumn Smith

Guest: Dr. Mark Hyman

Topics covered

• weight loss
• nutrition
• metabolic health
• ultra-processed foods
• insulin resistance
• diet quality

Keywords

• weight loss
• calories in calories out
• ultra-processed foods
• insulin resistance
• diet quality
• metabolic dysfunction
• hunger signals

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• The Supplement Industry Is Lying To You with Robyn Openshaw - Green Smoothie Girl · May 21, 2026 · 1h 4m
• Can Eating Meat Actually Be Healthy? with Dr. Drew Pinsky · May 12, 2026 · 1h 1m
• The Anti-Inflammatory Amino Acid You May Be Deficient In · May 5, 2026 · 1h 40m

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