Artificial Sweeteners and Cognitive Decline: Are Sugar Substitutes Sabotaging Brain Health? | Ep. 394

Artificial Sweeteners and Cognitive Decline: Are Sugar Substitutes Sabotaging Brain Health? | Ep. 394

May 5, 2026 · 1h 0m · Season 5 · Episode 54

About this episode

This episode discusses the potential negative effects of artificial sweeteners on brain health and cognitive decline, particularly in midlife and older adults.

Are artificial sweeteners helping us age well—or quietly working against our brain health? In this episode of The Aging Well Podcast , Jeff and Corbin unpack new research linking popular sugar substitutes to accelerated cognitive decline. While artificial sweeteners are often marketed as healthier alternatives to sugar, emerging evidence suggests the story may be more complex—especially for midlife and older adults concerned about dementia risk. Together, they explore the science behind the study, the broader metabolic and neurological implications of artificial sweeteners, and whether “natural” alternatives like honey, maple syrup, or stevia truly offer an advantage. This episode offers a balanced, science-based discussion to help listeners make informed decisions about sweeteners and long-term brain health. Article links: https://scitechdaily.com/popular-sugar-substitutes-linked-to-faster-cognitive-decline/ https://www.neurology.org/doi/10.1212/WNL.0000000000214023 Please, support The Aging Well Podcast by hitting the ‘like’ button, subscribing/following the podcast, sharing with a friend, and…. Tip Jar! All donations support this podcast to keep it going…

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