The Metabolic Roots of Cardiovascular Disease: A Vascular Surgeon's Perspective | Dr. Lily Johnston | The Metabolic Link Ep. 86
From The Metabolic Link by Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Field
January 27, 2026 · 1h 18m · Episode 86
About this episode
Dr. Lily Johnston discusses the potential reversal of the assumed sequence between plaque and arterial stiffness in cardiovascular disease.
What if the sequence we've always assumed—plaque causes arterial stiffness—is actually backwards? Dr. Lily Johnston proposes that impaired nitric oxide signaling may stiffen arteries first, creating the endothelial injury that then promotes plaque formation. Dr. Lily Johnston is a board-certified vascular surgeon and newly certified obesity medicine physician who bridges the operating room and metabolic medicine. After years of scraping plaque from arterial walls, she began questioning why su...
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Hosts: Dr. Dominic D'Agostino, Dr. Angela Poff, Victoria Field