Reversing Artery Plaque: 8 Supplements Ranked by the Evidence | Simon Hill, MSc

Reversing Artery Plaque: 8 Supplements Ranked by the Evidence | Simon Hill, MSc

June 29, 2026 · 1h 2m · Season 1

About this episode

Simon Hill discusses eight popular supplements and ranks them based on evidence for reversing artery plaque.

Can a supplement actually reverse the plaque in your arteries, or only slow it down? It is the question I am asked most, and after a 2024 scan revealed early plaque in my own left anterior descending artery, it became a personal one too. This is part two of my three-part series on reversing atherosclerosis. In this solo episode I work through eight of the most popular supplements and rank them by the strength of the human evidence, not the strength of the marketing. What we cover: Why pure EPA has by far the strongest evidence for regressing plaque, and what EVAPORATE, CHERRY, JELIS, and REDUCE-IT showed The REDUCE-IT versus STRENGTH debate, and why the form of omega-3 may matter as much as the dose Aged garlic extract and vitamin K2: what the imaging and calcification data suggest Niacin and the biomarker trap: raising "good" cholesterol without lowering risk Where CoQ10, berberine, nattokinase, and pomegranate extract really sit, plus a fact-check of a popular nattokinase claim My own plan after that scan, and a preview of part three on the pharmaceuticals Only one of these eight has strong evidence behind it, and even then it is a prescription rather than a tub from the…

People in this episode

Host: Simon Hill

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Mentioned in this episode

Products: EPA, Aged garlic extract, vitamin K2, Niacin, CoQ10, berberine, nattokinase, pomegranate extract

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