
Redefining Nutrition and Fitness with Mark Sisson
From The Strong New York Podcast by Kenny Santucci
February 25, 2026 · 34 min · Episode 66
About this episode
Kenny Santucci interviews Mark Sisson about redefining nutrition and fitness, exploring his journey and insights on health and entrepreneurship.
In this episode of the Strong New York Podcast, Kenny takes the show on the road to the LA Fit Expo to sit down with health and wellness legend Mark Sisson. Mark—New York Times bestselling author, former elite endurance athlete, and founder of Primal Kitchen—shares how injuries from running led him to rethink fitness, nutrition, and footwear, ultimately creating the Primal Blueprint and Primal Kitchen. He breaks down his simple framework for long-term health (diet, walking, lifting, sprinting, and sleep), explains why metabolic flexibility matters, and challenges mainstream nutrition “science.” We also dive into entrepreneurship, lessons learned building iconic brands, and why Mark launched his minimalist footwear company Peluva to address foot health from the ground up. 00:00 Live from LA Fit Expo: Welcome & Why Fitness Events Matter 00:26 Meet Mark Sisson: Athlete, Entrepreneur & Early Biohacker 01:25 From Running Injuries to Evolutionary Biology (and Building a Career) 02:17 Primal Kitchen Origin Story: Fixing Diet Through Better Sauces 03:33 Facing Rejection: Defending Paleo, Epigenetics & Self-Experimentation 05:55 Science, Money & Nutrition Confusion: Why…
People in this episode
Host: Kenny Santucci
Guest: Mark Sisson
Topics covered
- nutrition
- fitness
- entrepreneurship
- health
- metabolic flexibility
Keywords
- nutrition
- fitness
- Mark Sisson
- Primal Kitchen
- metabolic flexibility
- entrepreneurship
- health
Mentioned in this episode
Organizations: Primal Kitchen, Peluva
Books & works: Primal Blueprint
Places: New York, LA Fit Expo
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