Mar 13 2026 This Week in Cardiology

Mar 13 2026 This Week in Cardiology

From This Week in Cardiology by Medscape

March 13, 2026 · 32 min

About this episode

This episode discusses various topics in cardiology including beta-blockers in hypertrophic cardiomyopathy and the accuracy of smartwatches for atrial fibrillation detection.

Beta-blocker in non-obstructive hypertrophic cardiomyopathy, a head-to-head apixaban vs rivaroxaban RCT, diltiazem vs metoprolol combined with DOAC, and the accuracy of smart watches for AF are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only . To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Listener Feedback EMPATICC trial https://academic.oup.com/eurheartj/article/47/9/1034/8242490 II Beta-blocker in Non-obstructive HCM BB vs Calcium Channel Blocker in Non-obstructive HCM https://doi.org/10.1016/j.jacc.2025.11.028 RCT of Metoprolol in Patients With Obstructive HCM https://doi.org/10.1016/j.jacc.2021.07.065 III Apixaban vs Rivaroxaban for Bleeding Risk COBRRA Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2510703 AMPLIFY Trial (Apixaban) https://www.nejm.org/doi/10.1056/NEJMoa1302507 EINSTEIN Trial (Rivaroxaban) https://www.nejm.org/doi/full/10.1056/NEJMoa1007903 IV Diltiazem vs Metoprolol When Combined with DOAC Risk for Bleeding in AF Patients Using Apixaban or Rivaroxaban With Diltiazem https://www.acpjournals.org/doi/10.7326/ANNALS-25-01408 V Actual Clinical Use of…

People in this episode

Host: John Mandrola, MD

Topics covered

  • hypertrophic cardiomyopathy
  • anticoagulation
  • smartwatch accuracy
  • cardiology research
  • clinical trials

Keywords

  • hypertrophic cardiomyopathy
  • beta-blocker
  • apixaban
  • rivaroxaban
  • smart watches
  • clinical trials
  • diltiazem
  • metoprolol

Mentioned in this episode

Organizations: Medscape

Products: Beta-blocker, apixaban, rivaroxaban, diltiazem, metoprolol, DOAC, smart watches

Books & works: CIRCA-DOSE Original Trial, AMPLIFY Trial, EINSTEIN Trial, COBRRA Trial, Wearable Smartwatches for AF Detection After Ablation

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