Alexander Disease Research Update – Episode #27: Genotype-phenotype association for 14 GFAP variants
About this episode
Albee Messing, Mel Feany, and Natasha Snider discuss a recent publication on genotype-phenotype associations in Alexander disease.
Send us Fan Mail Albee Messing, Mel Feany, and Natasha Snider discuss the following recent publication: Genotype-phenotype association for 14 GFAP variants in Alexander disease. Neurology: Genetics. 11, e200270 (2025) [full text] Send your questions and feedback to: amessing@wisc.edu Help support research on Alexander Disease at the University of Wisconsin-Madison's Waisman Center: https://alexander-disease.waisman.wisc.edu/do...
People in this episode
Host: Albee Messing
Guests: Mel Feany, Natasha Snider
Topics covered
- Alexander Disease
- GFAP variants
- genotype-phenotype association
- neurology
- genetics
Keywords
- Alexander Disease
- GFAP variants
- genotype-phenotype
- neurology
- genetics
Mentioned in this episode
Organizations: University of Wisconsin-Madison's Waisman Center, Neurology: Genetics
Books & works: Genotype-phenotype association for 14 GFAP variants in Alexander disease
More episodes of Alexander Disease Research Update
- Alexander Disease Research Update – Episode #31: 1) Development of an AxD Severity Score, and 2) Peer review – please come home
- Alexander Disease Research Update – Episode #30: 1) Speech-language impairments, and 2) GFAP concentrations in CSF and blood
- Alexander Disease Research Update - Episode #29: Genotype-phenotype correlations, or does variant predict course?
- Alexander Disease Research Update - Episode #28: GDF15, nausea, vomiting, and "failure to thrive"
- Alexander Disease Research Update – Episode #26: Changes in gene expression and cognitive function in the rat model
- Alexander Disease Research Update – Episode #25: GFAP Variants in the UK Biobank - estimated prevalence of adult-onset AxD
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