Alexander Disease Research Update - Episode #29: Genotype-phenotype correlations, or does variant predict course?
About this episode
Albee Messing and Amanda Nagy discuss genotype-phenotype correlations of GFAP variants in type I Alexander disease subtypes.
Send us Fan Mail Albee Messing and Amanda Nagy discuss the following recent publication: [01:42] Genotype-phenotype correlations of GFAP variants in type I Alexander disease subtypes Molecular Genetics & Metabolism 147, 109689 (2026) Please send questions and feedback to: amessing@wisc.edu Help support research on Alexander Disease at the University of Wisconsin-Madison's Waisman Center: https://alexander-dise...
People in this episode
Host: Albee Messing
Guest: Amanda Nagy
Topics covered
- genotype-phenotype correlations
- Alexander disease
- GFAP variants
- type I Alexander disease subtypes
- recent publication
Keywords
- Alexander disease
- genotype-phenotype correlations
- GFAP variants
- type I
- Molecular Genetics & Metabolism
Mentioned in this episode
Books & works: Molecular Genetics & Metabolism
More episodes of Alexander Disease Research Update
- Alexander Disease Research Update – Episode #31: 1) Development of an AxD Severity Score, and 2) Peer review – please come home
- Alexander Disease Research Update – Episode #30: 1) Speech-language impairments, and 2) GFAP concentrations in CSF and blood
- Alexander Disease Research Update - Episode #28: GDF15, nausea, vomiting, and "failure to thrive"
- Alexander Disease Research Update – Episode #27: Genotype-phenotype association for 14 GFAP variants
- Alexander Disease Research Update – Episode #26: Changes in gene expression and cognitive function in the rat model
- Alexander Disease Research Update – Episode #25: GFAP Variants in the UK Biobank - estimated prevalence of adult-onset AxD
Explore listener stats, chart rankings, contacts and more on the Alexander Disease Research Update podcast page.