About this episode

The episode discusses metabolic alkalosis, focusing on chloride's role and related physiological studies.

We are a bit slappy at the beginning of the episode since we had just recorded our conversation with the Glaucomfleckens . References Chapter 18 Metabolic alkalosis!  Part 1 February 23, 2023 It is chloride depletion alkalosis, not contraction alkalosis classic review by Galla and Luke, the metabolic alkalosis mavens who review the role of chloride. On the mechanism by which chloride corrects metabolic alkalosis in man and this is the study when they induced a metabolic alkalosis and studied the effect of treating with KCl vs NaPhos and found the former (with chloride) reversed the alkalosis but not the sodium containing protocol.  Some elegant reports on the increased proximal reabsorption of bicarbonate above normal stimulated by Ang II.  Tubular transport responses to angiotensin | American Journal of Physiology-Renal Physiology Crosstalk between the renal sympathetic nerve and intrarenal angiotensin II modulates proximal tubular sodium reabsorption - Pontes - 2015 - Experimental Physiology - Wiley Online Library THE RENAL REGULATION OF ACID-BASE BALANCE IN MAN. III. THE REABSORPTION AND EXCRETION OF BICARBONATE 1949  this is the correct figure for 11.14…

Topics covered

• metabolic alkalosis
• chloride depletion
• acid-base balance
• renal physiology
• bicarbonate reabsorption

Keywords

• metabolic alkalosis
• chloride depletion
• bicarbonate
• renal physiology
• acid-base balance
• Ang II
• sodium reabsorption

Mentioned in this episode

Organizations: American Journal of Physiology-Renal Physiology, Experimental Physiology, PMC

Books & works: THE RENAL REGULATION OF ACID-BASE BALANCE IN MAN. III. THE REABSORPTION AND EXCRETION OF BICARBONATE, Metabolic Alkalosis, Crosstalk between the renal sympathetic nerve and intrarenal angiotensin II modulates proximal tubular sodium reabsorption, Masterful review

More episodes of Channel Your Enthusiasm

• Chapter Twenty One: Respiratory Alkalosis · March 24, 2026 · 1h 7m
• Chapter Nineteen: Metabolic Acidosis, part 3 · February 22, 2026 · 1h 58m
• Chapter Nineteen: Metabolic Acidosis, part 2 · October 11, 2025 · 1h 45m
• Chapter Eighteen: Metabolic Alkalosis, part 2 · July 22, 2025 · 1h 40m
• Chapter Nineteen: Metabolic Acidosis, The Show, part 1 · June 1, 2025 · 1h 45m
• Chapter Seventeen: Introduction to Simple and Mixed Acid-Base Disorders · February 21, 2025 · 1h 32m

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