50. Is PMDD a Histamine Problem? H1 and H2 Blockers Explained

50. Is PMDD a Histamine Problem? H1 and H2 Blockers Explained

June 15, 2026 · 23 min

About this episode

This episode explores the potential link between histamine and Premenstrual Dysphoric Disorder (PMDD).

Could histamine be contributing to Premenstrual Dysphoric Disorder (PMDD)? In this episode of The Histamine Well Podcast, Joanne explores the growing interest in the connection between PMDD, histamine intolerance, mast cell activation, and hormonal fluctuations. As more women report improvements in PMDD symptoms with antihistamines, the question is gaining attention: could histamine be a missing piece of the PMDD puzzle? Joanne breaks down the science behind the estrogen-histamine feedback lo...

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Host: Joanne Kennedy

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