About this episode

The episode discusses ferroptosis, an iron-dependent cell death pathway, and its implications in neurodegenerative diseases.

Send us Fan Mail Ferroptosis, an iron-dependent cell death pathway driven by lipid peroxidation; chronoferoptosis, in which chronic stress sensitizes neurons gradually. TOPICS DISCUSSED: Cell Death Pathways: Apoptosis proceeds through regulated steps with surface “eat me” signals that enable non-inflammatory clearance by phagocytes, whereas ferroptosis and related pathways release cellular contents that can amplify local damage and inflammation.Ferroptosis Discovery: Work on glutamate toxicit...

People in this episode

Host: Nick Jikomes

Guest: Pamela Maher

Mentioned in this episode

Books & works: Iron Overload & Lipid Peroxidation in Cell Death & Neurodegenerative Disease

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