Mind & Matter
by Nick Jikomes
Is this your podcast?Insights from recent episode analysis
Audience Interest
Podcast Focus
Publishing Consistency
Platform Reach
Insights are generated by CastFox AI using publicly available data, episode content, and proprietary models.
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Brands & references
Total monthly reach
Estimated from 1 chart position in 1 market.
By chart position
- 🇲🇾MY · Science#199500 to 3K
- Per-Episode Audience
Est. listeners per new episode within ~30 days
150 to 900🎙 Daily cadence·292 episodes·Last published 1w ago - Monthly Reach
Unique listeners across all episodes (30 days)
500 to 3K🇲🇾100% - Active Followers
Loyal subscribers who consistently listen
150 to 900
Market Insights
Platform Distribution
Reach across major podcast platforms, updated hourly
Total Followers
—
Total Plays
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Total Reviews
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* Data sourced directly from platform APIs and aggregated hourly across all major podcast directories.
On the show
From 21 epsHost
Recent guests
Recent episodes
Human Brain Evolution & Development | Christopher Walsh | Episode 306
Aug 28, 2026
1h 45m 15s
Endocannabinoid Biology in Health & Disease | Nephi Stella | Episode 305
Aug 20, 2026
1h 40m 40s
Mitochondria Peptides: MOTS-c, Humanin, Genetic Variation in Health & Disease | Pinchas Cohen | Episode 304
Aug 12, 2026
1h 46m 44s
Neuro-Immune Interactions: Pain, Inflammation, Peptides & Healing | Isaac Chiu | Episode 303
Aug 5, 2026
1h 44m 39s
MOTS-c & Mitochondrial Peptides in Health & Aging | David Lee | Episode 302
Jul 30, 2026
1h 50m 05s
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| Date | Episode | Topics | Guests | Brands | Places | Keywords | Sponsor | Length | |
|---|---|---|---|---|---|---|---|---|---|
| 8/28/26 |  Human Brain Evolution & Development | Christopher Walsh | Episode 306 | Send us Fan Mail How genomics is used to study what makes a human brain, and how genetically damaged neurons get removed. TOPICS DISCUSSED: Scale & Size: A human brain is about three times a chimpanzee brain by mass, but the larger change is extra association cortex and extra upper-layer circuits that talk mostly to other cortex.When Development Ends: Most cortical neurons are born before birth. Myelin and other glia keep forming into the twenties. Synapses keep changing after that.Broken... | 1h 45m 15s | ||||||
| 8/20/26 |  Endocannabinoid Biology in Health & Disease | Nephi Stella | Episode 305 | Send us Fan Mail The biology of endogenous cannabinoids & history of cannabinoid-based therapeutics TOPICS DISCUSSED: Anandamide vs 2-AG: The two major endocannabinoids with a shared arachidonic acid backbone but distinct head groups biological roles.On-demand production: Calcium-dependent enzymes release cannabinoids from membranes in response to neuronal activity patterns.Trafficking: Fatty acid binding proteins and extracellular microvesicles traffic endocannabinoids within and between... | 1h 40m 40s | ||||||
| 8/12/26 |  Mitochondria Peptides: MOTS-c, Humanin, Genetic Variation in Health & Disease | Pinchas Cohen | Episode 304 | Send us Fan Mail Mitochondrial peptides act as stress signals that regulate metabolism, muscle mass, and neurodegeneration. TOPICS DISCUSSED: Mitochondria as Communication Hubs: Beyond ATP production, mitochondria encode peptides that regulate cell death, immunity, and inter-organ communication.Humanin Discovery: Identified independently by three labs; neuroprotective, longevity-linked, and capable of neutralizing APOE4 effects via a rare Jewish variant.Ethnic Genetic Variants: Ancestry-speci... | 1h 46m 44s | ||||||
| 8/5/26 |  Neuro-Immune Interactions: Pain, Inflammation, Peptides & Healing | Isaac Chiu | Episode 303 | Send us Fan Mail How the nervous and immune systems communicate, using peptides and other signals, to regulate pain, itch, and inflammation. TOPICS DISCUSSED: Nociception & Pathogens: Sensory neurons detect bacterial toxins within seconds, enabling rapid host-defense coordination ahead of immune-cell recruitment.CGRP & neutrophils: Nociceptor-release the peptide CGRP, which blocks neutrophil (immune cell) recruitment; pathogens exploit this in necrotizing fasciitis and meningitis.Pain... | 1h 44m 39s | ||||||
| 7/30/26 |  MOTS-c & Mitochondrial Peptides in Health & Aging | David Lee | Episode 302 | Send us Fan Mail Mitochondrial peptide MOTS-c is a stress-induced signal that reprograms cell metabolism. TOPICS DISCUSSED: Mitochondrial Roles: Not just ATP production, but “speaker of the house” via communication molecules that “talk” to the rest of the cell.Origin of Communication: Mitochondrial peptides were likely co-opted from ancient antimicrobial factors to synchronize nuclear and mitochondrial genomes.MOTC Discovery: Identified in mitochondrial ribosomal RNA regions linked to interfe... | 1h 50m 05s | ||||||
| 7/22/26 |  Peptides & GHK-Copper in Skin Health | Rahi Sarbaziha | Episode 301 | Send us Fan Mail GHK-Copper and peptides in skin care, aging, and general health. TOPICS DISCUSSED: Endogenous Decline: GHK-copper levels peak in young adulthood then fall with age, reducing natural support for skin repair and collagen maintenance.Skin Penetration: Effective topical delivery depends on molecular size under and fat solubility, often improved by procedures such as microneedling that briefly disrupt the barrier.Mechanisms of Action: The peptide upregulates fibroblasts and vascul... | 50m 29s | ||||||
| 7/15/26 | Blood-Brain BarrierPeptides+4 | William Banks | Mind & MatterNick Jikomes | — | blood-brain barrierpeptides+6 | — | 1h 44m 56s | ||
| 7/8/26 | Ferroptosiscell death pathways+4 | Pamela Maher | Iron Overload & Lipid Peroxidation in Cell Death & Neurodegenerative Disease | — | ferroptosiscell death+5 | — | 1h 42m 47s | ||
| 6/30/26 | ObesityDiabetes+4 | Katrin Svensson | PCSKGLP-1+1 | pancreasgut | GLP-1peptides+5 | — | 1h 34m 35s | ||
| 6/30/26 |  GLP-1s & Novel Peptides in Obesity, Diabetes & Metabolic Health | Katrin Svensson | Episode 298 | Send us Fan Mail Endogenous peptide diversity, GLP-1 drugs, and methods for novel peptide discovery. TOPICS DISCUSSED: Peptide Structure & Production: Short amino acid chains (3-50 residues) cleaved from larger precursors by PCSK enzymes, stored in dense-core vesicles, and released upon stimuli rather than acting as folded enzymes like proteins.Tissue-Specific Processing: The same precursor yields different peptides by tissue; preproglucagon produces glucagon in pancreas but GLP-1 in gut ... | 1h 34m 35s | ||||||
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| 6/18/26 | deuteriummetabolic water+3 | Gábor Somlyai | deuteriummetabolic water+5 | — | deuteriummetabolic water+5 | — | 1h 33m 21s | ||
| 6/11/26 | AntioxidantsCancer Research+3 | Isaac Harris | vitamin Ebeta-carotene+1 | — | antioxidantscancer+3 | — | 57m 22s | ||
| 6/4/26 | Fructose MetabolismObesity+5 | Richard Johnson | — | — | fructosemetabolism+7 | — | 1h 36m 17s | ||
| 6/4/26 |  Fructose Metabolism in Obesity, Dementia, Evolution | Richard Johnson | Episode 295 | Send us Fan Mail Fructose survival hypothesis: how fructose metabolism in the liver triggers ATP depletion, uric acid production, oxidative stress, lipogenesis & leptin resistance. TOPICS DISCUSSED: Glucose vs Fructose Metabolism: Fructose is rapidly metabolized in the liver by fructokinase without feedback, causing ATP depletion and uric acid production, unlike glucose metabolism.Liver Effects: Fructose induces uric acid production, NADPH oxidase activation, mitochondrial oxidative stres... | 1h 36m 17s | ||||||
| 5/27/26 | seed oilsinflammation+4 | — | seed oilssunflower+3 | — | seed oilsinflammation+5 | — | 1h 12m 50s | ||
| 5/27/26 | How to Lie With Science: Seed Oils & Inflammation | Livestream 1 | Send us Fan Mail Deep-dive into a 2026 cardiology review paper claiming seed oils reduce inflammation, exposing misrepresentations of cited clinical trials, and detailing how oxidized Ω-6 fats trigger inflammation. Companion article: Click HERE TOPICS DISCUSSED: Seed Oil Profiles: Typical seed oils like sunflower are high in linoleic acid (omega-6 PUFA), while canola is higher in monounsaturated fats and resembles olive oil.Review Paper Critique: The 2026 JACC review falsely claims sunflower ... | 1h 12m 50s | ||||||
| 5/22/26 | genetic diversityfat metabolism+4 | Floyd Chilton | linoleic acidomega-3 ALA+7 | — | linoleic acidomega-6+5 | — | 1h 51m 40s | ||
| 5/15/26 | neurosteroidsbrain health+5 | Sherwood Brown | pregnenolonecorticosteroids+5 | — | pregnenolonecorticosteroids+6 | — | 1h 01m 39s | ||
| 5/8/26 | omega-3 fatshuman health+4 | Bill Harris | ω-3 SupplementsEPA+3 | — | omega-3EPA+5 | — | 1h 46m 16s | ||
| 5/1/26 | dietary fatty acidsinflammation+4 | Philip Calder | soybean oilfish oil+6 | — | omega polyunsaturated fatsinflammation+3 | — | 1h 55m 20s | ||
| 4/24/26 | Alzheimer's diseaseneurodegeneration+4 | Andrew Pieper | Alzheimer's diseaseamyloid plaques+3 | — | Alzheimer'sneurodegeneration+5 | — | 1h 24m 12s | ||
| 4/17/26 | parental exerciseoffspring health+4 | Kristin Stanford | — | — | exerciseoffspring+5 | — | 50m 54s | ||
| 4/10/26 | vagus nerveinflammation+3 | Kevin Tracey | bioelectronic medicineanti-cytokine drugs | heart diseasediabetes | vagus nerveinflammation+4 | — | 1h 59m 41s | ||
| 4/3/26 | circadian rhythmsmitochondrial function+5 | Alexis Cowan | SCN | — | lightcircadian rhythms+8 | — | 1h 50m 46s | ||
| 3/29/26 | sleepoxidative stress+3 | Amita Sehgal | Drosophila | — | sleepoxidized fats+5 | — | 1h 09m 18s | ||
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Chart history for Mind & Matter
Peaked at #199 in MY, currently #199 in MY.
| Market | Genre | Peak | Current | Trend |
|---|---|---|---|---|
| MY | — | #199 | #199 | — |
Chart Positions
1 placement across 1 market.
Chart Positions
1 placement across 1 market.