About this episode

The episode discusses the structure and function of the blood-brain barrier, including how various substances cross it and its implications for health and disease.

Send us Fan Mail Blood-brain barrier as a dynamic interface allowing selective passage of nutrients, peptides, and gut hormones. TOPICS DISCUSSED: Blood-Brain Barrier Structure: Capillary endothelial cells with tight junctions, absent fenestrae, and minimal vesicles create a selective interface; supported by astrocytes and pericytes.Crossing Mechanisms: Lipid-soluble small molecules diffuse passively; glucose, amino acids, and regulatory peptides use saturable transporters whose rates vary by...

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Host: Nick Jikomes

Guest: William Banks

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Organizations: Mind & Matter

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