104. How Light Shapes Hormones with Sarah Kleiner

104. How Light Shapes Hormones with Sarah Kleiner

March 4, 2026 · 1h 4m

About this episode

Mona Sharma and Sarah Kleiner discuss how circadian rhythm influences women's hormones and practical ways to restore hormonal balance.

Perimenopause can feel like your body is sending mixed signals. Appetite shifts. Sleep changes. Stress tolerance shrinks. And when labs come back “normal,” it can leave you feeling unheard in your own experience. In this episode, I sit down with Sarah Kleiner to explore circadian rhythm as a foundational regulator of women’s hormones. We unpack leptin as a master safety signal that influences thyroid function, reproductive hormones, metabolism, and appetite. We also discuss how artificial light, screens, chronic stress, and restrictive dieting can blunt this signaling, especially in midlife when resilience narrows. This conversation reframes hormone imbalance through the lens of rhythm and nervous system regulation rather than quick fixes. You’ll walk away with simple, practical ways to begin restoring amplitude to your day, starting with light, timing, and nourishment. Sarah Kleiner is the founder of Sarah Kleiner Wellness and the creator of My Circadian App. What's Discussed: (00:00) Midlife as recalibration and why hormones reflect circadian rhythm and safety (07:30) Leptin as a master signal and how it informs thyroid, metabolism, and fertility (15:00) Cortisol, melatonin…

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