SIBO Die-Off Explained: Why You Feel Worse Before You Feel Better (And What To Do About It)

SIBO Die-Off Explained: Why You Feel Worse Before You Feel Better (And What To Do About It)

April 21, 2026 · 37 min

About this episode

This episode explains the die-off reaction during SIBO recovery and why symptoms may worsen before improvement.

Send us Fan Mail If you’ve ever started antibiotics, herbals, or an elemental diet, and suddenly felt more bloated, more fatigued, and completely off, this episode will explain exactly why. We’re breaking down one of the most misunderstood parts of SIBO recovery: die-off (Herxheimer reaction). You’ll learn: What endotoxins are and why they trigger symptomsWhy SIBO die-off affects your whole body (not just your gut)The 2 main types of die-off symptoms (digestive vs systemic)The typical timelin...

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