About this episode

This episode discusses the COMT gene and its impact on women's hormonal health, anxiety, and PMS during perimenopause.

☎️ Book Your COMPLEMENTARY CONSULTATION and CALORIE CALCULATION Call: https://calendly.com/d/2p8-mxx-dgf/free-consultation-call-zoom⁠⁠⁠⁠⁠⁠ 👉 MTHFR, Methylation & Menopause: The Hidden Link Between Genes, Detox, and Fat Loss | MMP Ep. 246: https://youtu.be/8ZBcydkp-HI 👉 DUTCH test info page: https://vitalityoet.lovable.app/ Your anxiety, your severe PMS, your flat mood in perimenopause — there is a gene that may be running all of it. In this episode of the Metabolism and Menopause Podcast, Stephanie Crassweller breaks down the COMT gene (catechol-O-methyltransferase) — one of the most clinically significant genetic factors for women's hormonal health, and one almost nobody is talking about. You'll learn: what COMT does in the body, why its variants — Slow, Intermediate, and Fast — produce completely opposite symptoms, how estrogen directly modulates COMT activity across the cycle and into perimenopause, and what targeted nutritional and lifestyle support looks like for each type. Includes a self-identification checklist, DUTCH test guidance, and practical protocols you can start today. 🧠 Not Sure Where to Start? Take The Fat Loss Fix Quiz 👉…

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