HRT Isn’t Enough: Why You Still Need to Build Muscle | Solo

HRT Isn’t Enough: Why You Still Need to Build Muscle | Solo

April 27, 2026 · 51 min

About this episode

Dr. Tyna Moore discusses the complexities of estrogen's role in muscle health and the importance of strength training, especially for women over 40.

EP. 258: Get Strong with Me Inside my NEW Strength Vault: https://www.drtyna.com/offers/G33fSdvSIn this episode, I’m breaking down one of the most frustrating conversations happening in women’s health right now, the claim that estrogen and hormone replacement therapy don’t support muscle mass. The reality is more nuanced. I walk through what the current research actually shows, where it’s strong, where it’s inconsistent, and how estrogen interacts with skeletal muscle at a physiological level. We’re talking about estrogen receptors in muscle, mitochondrial function, anabolic signaling, insulin resistance, and why outcomes around muscle are often context-dependent. I also share what I’ve observed clinically after decades of working in a musculoskeletal setting, and how factors like metabolic health, training status, and overall tissue quality may influence how hormone therapy plays out in the real world. This episode isn’t about claiming HRT builds muscle. It’s about understanding how estrogen affects muscle biology, and why strength training remains a non-negotiable piece of the equation. Topics Discussed: → Estrogen and muscle growth → HRT and menopause fitness → Strength…

Sponsors

Ogee

More episodes of The Dr. Tyna Show

Explore listener stats, chart rankings, contacts and more on the The Dr. Tyna Show podcast page.