Making Sense of Touch

About this episode

The episode discusses new lab models for studying Merkel cells using various tissue cultures and organoids.

Our guests today created new lab models to study Merkel cells using mouse whisker tissue cultures, mouse skin organoids, and human skin organoids. These models allowed them to study Merkel cells as they develop, validate the role of known signaling pathways, and even identify some new ones. Their work provides easier access to Merkel cells for future studies including disease models to understand the pathophysiology of these cells. Guests Ying Xiao, PhD, Sir Run Run Shaw Hospital, Scho...

People in this episode

Guest: Ying Xiao, PhD

Topics covered

• Merkel cells
• mouse models
• skin organoids
• signaling pathways
• disease models

Keywords

• Merkel cells
• mouse whisker tissue
• skin organoids
• signaling pathways
• pathophysiology

Mentioned in this episode

Organizations: Sir Run Run Shaw Hospital, ISSCR

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