Movin’ On Out: Mobilizing HSCs From The Bone Marrow
About this episode
This episode discusses the mobilization of hematopoietic stem cells from the bone marrow to the bloodstream for transplantation therapy.
Hematopoietic stem cells (HSCs) normally reside in the bone marrow niche but can traffic across the bone marrow endothelium into the bloodstream to populate different niches. This process of HSC mobilization from the bone marrow to the blood, is an increasingly favored procedure to obtain HSCs for hematopoietic cell transplantation therapy. Though mobilization is robust in many donors due to years of refined protocols and drug combinations, the process remains difficult or contraindicated amo...
People in this episode
Host: Janet Rossant
Mentioned in this episode
Organizations: ISSCR
Products: Hematopoietic stem cells (HSCs)
Places: bone marrow, blood
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