Episode 3: A View On mRNA Encapsulation

About this episode

This episode discusses the future of mRNA therapies and the innovative techniques driving their development.

Driving Innovation Through Collaboration: The Future of mRNA Therapies In this episode, we are joined by three experts—Christoph Hein (Fraunhofer IPK), Bernhard Bobusch (FDX Fluid Dynamix), and Sönke Stocker (Lonza)—to explore how advanced fluidics, encapsulation techniques, and a truly collaborative approach are paving the way for potential solid-tumor vaccines now in preclinical trials. When you think about mRNA-based vaccines, have you ever considered the complex route these microscopic instructions must travel to deliver their life-changing code? This journey, essential for the therapy’s success, lies at the core of pharmaceutical research—where the challenge is to maximize stability and “bioavailability” so that each dose effectively reaches its cellular target. By enclosing mRNA within lipid nanoparticles (LNPs) using sophisticated mixing technologies, scientists can create the next generation of therapies—tailored to each patient’s needs. From prophylactic vaccines to personalized cancer treatments for solid tumors, these breakthroughs promise not only more effective but also safer medical solutions. In this episode, we spotlight FDmiX®, a groundbreaking mixer platform…

People in this episode

Host: Martina Ribar Hestericová

Guests: Christoph Hein, Bernhard Bobusch, Sönke Stocker

Topics covered

• mRNA therapies
• encapsulation techniques
• solid-tumor vaccines
• pharmaceutical research
• lipid nanoparticles
• personalized cancer treatments

Keywords

• mRNA
• vaccines
• lipid nanoparticles
• cancer treatments
• bioavailability
• pharmaceutical research
• solid tumors
• encapsulation

Mentioned in this episode

Organizations: Fraunhofer IPK, FDX Fluid Dynamix, Lonza

Products: FDmiX®

More episodes of A view on

• Episode 10: A View On Manufacturing Hard-to-manufacture Molecules · March 30, 2026 · 14 min
• Episode 9: A View On Innovating Drug Development and Manufacturing · December 15, 2025 · 17 min
• Episode 8: A View On Process Analytical Technologies · November 11, 2025 · 19 min
• Episode 7: A View On Spray-Drying mRNA-based Therapies · July 28, 2025 · 23 min
• Episode 6: A View On Improving Microbial Manufacturing · July 2, 2025 · 18 min
• Episode 5: A View On Smart Capsule Technology · May 27, 2025 · 20 min