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Est. listeners per new episode within ~30 days
10,001 - 25,000 - Monthly Reach
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25,001 - 75,000 - Active Followers
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15,001 - 40,000
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On the show
From 11 epsHosts
Recent guests
Recent episodes
Why We Need Continual Learning
Apr 28, 2026
18m 38s
The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie
Apr 21, 2026
59m 37s
Rethinking Git for the Age of Coding Agents with GitHub Cofounder Scott Chacon
Apr 8, 2026
47m 05s
How AI Is Reshaping IT Services from the Inside
Apr 1, 2026
34m 28s
Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding
Mar 24, 2026
52m 53s
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| Date | Episode | Topics | Guests | Brands | Places | Keywords | Sponsor | Length | |
|---|---|---|---|---|---|---|---|---|---|
| 4/28/26 | Why We Need Continual Learning✨ | AI systemscontinual learning+3 | Malika Aubakirova | a16z | — | AIcontinual learning+3 | — | 18m 38s | |
| 4/21/26 | The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie✨ | enterprise softwarecoding agents+4 | Aaron Levie | Box | — | enterprise softwareagents+5 | — | 59m 37s | |
| 4/8/26 | Rethinking Git for the Age of Coding Agents with GitHub Cofounder Scott Chacon✨ | version controlAI agents+3 | Scott Chacon | GitHubGitButler | — | GitGitHub+5 | — | 47m 05s | |
| 4/1/26 | How AI Is Reshaping IT Services from the Inside✨ | AIIT services+3 | Peter Doyle | Treeline | — | AIIT services+5 | — | 34m 28s | |
| 3/24/26 | Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding✨ | StripeAPI design+4 | Patrick Collison | SmalltalkLisp+5 | — | StripeAPI design+5 | — | 52m 53s | |
| 3/19/26 | OpenClaw: Why the Internet Isn't Built for AI Agents✨ | AI agentsidentity+4 | Yoko LiGuido Appenzeller+1 | OpenClawGmail+2 | — | OpenClawAI assistant+5 | — | 47m 10s | |
| 3/17/26 | What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado✨ | LLMsAGI+4 | Vishal Misra | — | — | LLMsAGI+5 | — | 47m 35s | |
| 3/10/26 | Replit's CEO on Vibe Coding, Wealth Building, and What Most People Get Wrong About AI✨ | AIsoftware development+4 | Amjad Masad | Replit | — | AIReplit+6 | — | 1h 39m 18s | |
| 3/3/26 | Jack Altman & Martin Casado on the Future of VC✨ | venture capitalAI infrastructure+3 | Martin Casado | a16z | — | venture capitalAI+4 | — | 53m 28s | |
| 2/24/26 | AI’s Capital Flywheel: Models, Money, and the Future of Power✨ | AI investment cycleventure capital+4 | Martin CasadoSarah Wang | a16zLatent Space | — | AIventure capital+5 | — | 57m 52s | |
Want analysis for the episodes below?Free for Pro Submit a request, we'll have your selected episodes analyzed within an hour. Free, at no cost to you, for Pro users. | |||||||||
| 2/19/26 | Durable Execution and the Infrastructure Powering AI Agents✨ | durable executionAI agents+4 | Samar Abbas | CodexStory+3 | — | durable executionAI infrastructure+5 | — | 1h 03m 46s | |
| 2/17/26 | ![]() Evals, Feedback Loops, and the Engineering That Makes AI Work | Martin Casado speaks with Ankur Goyal, founder and CEO of Braintrust, about where engineering actually matters in AI and where it doesn't. They cover the open source vs closed source model cycle, why Chinese models are gaining ground faster than spending suggests, whether AI demand will eventually saturate, and the Bash vs SQL benchmark that challenges the "just give it a computer" approach to agents. | — | ||||||
| 2/10/26 | ![]() Sam Altman on Sora, Energy, and Building an AI Empire | Sam Altman has led OpenAI from its founding as a research nonprofit in 2015 to becoming the most valuable startup in the world ten years later. In this episode, a16z Cofounder Ben Horowitz and General Partner Erik Torenberg sit down with Sam to discuss the core thesis behind OpenAI’s disparate bets, why they released Sora, how they use models internally, the best AI evals, and where we’re going from here. | — | ||||||
| 2/3/26 | ![]() Why This Isn't the Dot-Com Bubble | Martin Casado on WSJ's BOLD NAMES | Christopher Mims and Tim Higgins of the Wall Street Journal sit down with a16z General Partner Martin Casado on WSJ’s Bold Names to ask whether the AI spending boom is a bubble waiting to burst. Martin explains why the fundamentals differ dramatically from the dot-com era—when WorldCom had $40 billion in debt versus today's tech giants with hundreds of billions on their balance sheets—and why a speculative valuation correction shouldn't be confused with systemic collapse. They also discuss where a16z sees opportunity in the "long tail" of AI companies beyond the state-of-the-art large language models. | — | ||||||
| 1/27/26 | ![]() Martin Casado on the Demand Forces Behind AI | In this feed drop from The Six Five Pod, a16z General Partner Martin Casado discusses how AI is changing infrastructure, software, and enterprise purchasing. He explains why current constraints are driven less by technical limits and more by regulation, particularly around power, data centers, and compute expansion. The episode also covers how AI is affecting software development, lowering the barrier to coding without eliminating the need for experienced engineers, and how agent-driven tools may shift infrastructure decision-making away from humans. | — | ||||||
| 1/23/26 | ![]() How Mintlify Is Rebuilding Documentation for Coding Agents | Mintlify is a documentation platform built by cofounders Han Wang and Hahnbee Lee to help teams create and maintain developer docs. In this episode, Andreessen Horowitz general partners Jennifer Li and Yoko Li speak with Han and Hahnbee about how coding agents are changing what “good docs” mean, shifting documentation from a human-only resource into infrastructure that powers AI tools, support agents, and internal knowledge workflows. They share Mintlify’s early journey, including eight pivots, the two-day prototype that landed their first customer, and the “do things that don’t scale” sales motion that helped them win early traction. The conversation also covers why docs go out of date, what “self-healing” documentation requires to actually work, and how serving fast-moving customers has shaped both their product priorities and their pace. | — | ||||||
| 1/22/26 | ![]() Inferact: Building the Infrastructure That Runs Modern AI | Inferact is a new AI infrastructure company founded by the creators and core maintainers of vLLM. Its mission is to build a universal, open-source inference layer that makes large AI models faster, cheaper, and more reliable to run across any hardware, model architecture, or deployment environment. Together, they broke down how modern AI models are actually run in production, why “inference” has quietly become one of the hardest problems in AI infrastructure, and how the open-source project vLLM emerged to solve it. The conversation also looked at why the vLLM team started Inferact and their vision for a universal inference layer that can run any model, on any chip, efficiently. | — | ||||||
| 1/20/26 | ![]() How Should AI Be Regulated? Use vs. Development | In this episode, Chief Legal & Policy Officer Jai Ramaswamy, Matt Perault, and a16z General Partner Martin Casado take a first-principles look at AI regulation, arguing that policymakers should focus on regulating harmful uses rather than model development until AI’s marginal risks are better understood. Drawing on decades of software governance debates, from encryption to cybersecurity, they contend that development-level rules are hard to define, easy to loophole, and likely to become obsolete in a fast-moving field where even the definition of “AI” remains unstable. They also unpack how regulatory uncertainty already creates real-world consequences by chilling open-source releases, advantaging well-resourced incumbents over startups, and pushing the next generation of builders and researchers toward Chinese open models, making the case for evidence-based, technology-neutral policy that protects against bad behavior without stifling innovation. | — | ||||||
| 1/13/26 | ![]() Michael Truell: How Cursor Builds at the Speed of AI | When four MIT grads decided to build a code editor while everyone else was building AI agents, they created the fastest-growing developer tool ever built. Cursor CEO Michael Truell joins a16z’s Martin Casado to discuss the deliberate constraints that led to breakthroughs: why they rejected the "democratization" narrative to focus on power users, how their 2-day work trials test for agency over credentials, and the strategic decision to own the editor when conventional wisdom said it was impossible. | — | ||||||
| 1/6/26 | ![]() Dylan Patel on the AI Chip Race - NVIDIA, Intel & the US Government | Nvidia’s $5 billion investment in Intel is one of the biggest surprises in semiconductors in years. Two longtime rivals are now teaming up, and the ripple effects could reshape AI, cloud, and the global chip race. To make sense of it all, Erik Torenberg is joined by Dylan Patel, chief analyst at SemiAnalysis, joins Sarah Wang, general partner at a16z, and Guido Appenzeller, a16z partner and former CTO of Intel’s Data Center and AI business unit. Together, they dig into what the deal means for Nvidia, Intel, AMD, ARM, and Huawei; the state of US-China tech bans; Nvidia’s moat and Jensen Huang’s leadership; and the future of GPUs, mega data centers, and AI infrastructure. | — | ||||||
| 12/30/25 | ![]() Feed Drop from The Generalist: Why a16z's Martin Casado believes the AI boom still has years to run | This episode is a special replay from The Generalist Podcast, featuring a conversation with a16z General Partner Martin Casado. Martin has lived through multiple tech waves as a founder, researcher, and investor, and in this discussion he shares how he thinks about the AI boom, why he believes we’re still early in the cycle, and how a market-first lens shapes his approach to investing. They also dig into the mechanics behind the scenes: why AI coding could become a multi-trillion-dollar market, how a16z evolved from a small generalist firm into a specialized organization, the growing role of open-source models, and why Martin believes AGI debates often obscure more meaningful questions about how technology actually creates value. | — | ||||||
| 12/23/25 | ![]() Fei-Fei Li: World Models and the Multiverse | What if the next leap in artificial intelligence isn’t about better language—but better understanding of space? In this episode, a16z General Partner Erik Torenberg moderates a conversation with Fei-Fei Li, cofounder and CEO of World Labs, and a16z General Partner Martin Casado, an early investor in the company. Together, they dive into the concept of world models—AI systems that can understand and reason about the 3D, physical world, not just generate text. Often called the “godmother of AI,” Fei-Fei explains why spatial intelligence is a fundamental and still-missing piece of today’s AI—and why she’s building an entire company to solve it. Martin shares how he and Fei-Fei aligned on this vision long before it became fashionable, and why it could reshape the future of robotics, creativity, and computational interfaces. From the limits of LLMs to the promise of embodied intelligence, this conversation blends personal stories with deep technical insights—exploring what it really means to build AI that understands the real (and virtual) world. | — | ||||||
| 12/16/25 | ![]() Building the “See Something, Say Something” AI for Every Camera | a16z's Martin Casado sits down with Shikhar Shrestha, CEO and cofounder of Ambient, the company bringing agentic AI to physical security. Shikhar shares how a traumatic armed robbery at age 12—and a security camera that no one was watching—sparked his mission to make every camera intelligent. They discuss how Ambient's AI monitors camera feeds in real-time to detect threats and prevent incidents before they happen, navigating COVID as a physical security company, building their own reasoning VLM called Pulsar, and why the future of security is AI not just detecting threats but automatically responding to them. | — | ||||||
| 12/10/25 | ![]() The AI That Found A Bug In The World’s Most Audited Code | Matt Knight spent five years as OpenAI’s CISO. Now he runs what colleagues call “the most interesting job at the company”: leading Aardvark, an AI agent that finds security vulnerabilities the way a human researcher would—by reading code, writing tests, and proposing patches. It recently found a memory corruption bug in OpenSSH, one of the most heavily audited codebases in existence. | — | ||||||
| 12/5/25 | ![]() The Death of Data Gatekeeping: AI Makes Everyone An Analyst | Hex Cofounder | Most companies still rely on dashboards to understand their data, even though AI now offers new ways to ask questions and explore information. Barry McCardel, CEO of Hex and former engineer at Palantir, joins a16z General Partner Sarah Wang to discuss how agent workflows, conversational interfaces, and context-aware models are reshaping analysis. Barry also explains how Hex aims to make everyone a data person by unifying analysis and AI in one workflow, and he reflects on his post about getting rid of their AI product team and the process behind Hex’s funny launch videos. | — | ||||||
Showing 25 of 94
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