
In Me or Around Me? Genetics vs. Environment in Lung Cancer
From Backstage @ Upstage by Upstage Lung Cancer
April 25, 2026 · 36 min · Season 1 · Episode 56
About this episode
The episode explores the interplay between genetics and environment in lung cancer risk, featuring insights from leading medical experts.
HOST: Hildy Grossman, CO-HOST: Jordan Rich GUESTS: Lecia Sequist, MD and Allison Chang, MD, Ph.D. We are building on our previous "All in the Family" episode, with Jaclyn Lo Piccolo, MD, Ph.D., Pasi Janne, MD, Ph.D., of the Dana Farber Cancer Institute and Jill Feldman from EGFR Resisters. To look deeper into how a family history of lung cancer might increase the risk for other members, we invited Drs. Lecia Sequist and Allison Chang from Mass General Hospital to discuss their latest research on risk factors and the role of family history in lung cancer. We examine the current array of diagnostic tools—from CT scans to germline genetic testing—and the mystery of why some family members are more vulnerable to environmental pollutants than others. Tune in to see how Drs. Sequist and Chang are using AI- driven CT analysis to identify risk in those with a family history of lung cancer and learn if you qualify to participate in their
People in this episode
Host: Hildy Grossman
Guests: Lecia Sequist, MD, Allison Chang, MD, Ph.D.
Topics covered
- genetics
- environment
- lung cancer
- family history
- diagnostic tools
- AI-driven analysis
Keywords
- lung cancer
- genetics
- environment
- family history
- diagnostic tools
- AI analysis
- risk factors
Mentioned in this episode
Organizations: Dana Farber Cancer Institute, Mass General Hospital, EGFR Resisters
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