BENCH to BEDSIDE

The Innovate, Design, Engineer, and Accelerate (IDEA) Lab will be a centerpiece of the Morgan Center for Research and Innovation at Children's Hospital of Philadelphia Research Institute. Researchers will have the on-campus ability to shape their creativity with resources for biofabrication. In this episode of the Bench to Bedside podcast, host Susan Furth, MD, PhD, invited the leader of the IDEA Lab, Elizabeth Silvestro, PhD, to learn more about the manufacturing lab’s capabilities and how it's pushing research to new engineering heights.

With an anticipated end-of-year opening of the 17-story, 350,000 square-foot Morgan Center for Research & Innovation, Dr. Sue Furth invited Donald Moore, senior vice president of CHOP’s Real Estate, Facilities, and Operations, to discuss how the project came to fruition, what researchers and the Philadelphia community can look forward to experiencing, and how Moore helped facilitate the project to its completion.

In the first part of our Bench to Bedside series focused on the transformative power of donations, gifts, and investments to support pediatric research, Monica Taylor Lotty, Children's Hospital of Philadelphia’s Chief Development Officer, shares the deeply heartfelt reasons behind philanthropy, which, at its core, “literally means love of humanity”. Learn more about how you can support children's health by contacting the CHOP Foundation: https://www.chop.edu/giving

In the second part of our Explore the Cores series, Florin Tuluc, MD, PhD, Director of the Flow Cytometry Core Laboratory at CHOP Research Institute, sits down with host Susan Furth, MD, PhD, Chief Scientific Officer, to talk about what makes the Flow Lab a unique and valuable resource for the CHOP scientific community. Spoiler: It’s one-part state-of-the-art technology and two parts a team of incredible individuals with a passion for pediatric health.

Precision medicine, also known as personalized medicine, has revolutionized how physicians and scientists treat and study disease. According to Theodore Laetsch, MD, an oncologist at Children’s Hospital of Philadelphia, this ability to track and tailor individual patients’ unique genetic signatures has the most transformative potential in pediatric cancer. In this episode of Bench to Bedside, Dr. Laetsch shares how his new Frontier Program, the Center for Precision Medicine for High-risk Pediatric Cancer, harnesses advanced technologies and a growing multi omics database to optimize outcomes for childhood cancer patients.

With a stroll down the hallway at Children’s Hospital of Philadelphia, you run into a tremendous knowledge base and expertise to help answer challenging scientific questions in pediatrics. Lindsey George, MD, PhD, director of the Novel Therapeutics for Bleeding Disorders Frontier Program, shares how this combined clinical experience in gene therapy for hemophilia and in other related bleeding disorders leads toward innovative approaches.

“Be bold. Solve important problems,” shares Bench to Bedside guest, Flaura Winston, MD, PhD, founder and co-scientific director of the Center for Injury Research and Prevention. Hear how this Center of Emphasis takes a research action to impact approach when it comes to preventing injury in children.

Join the conversation with Hakon Hakonarson, MD, PhD, founding director of the Center for Applied Genomics, where scientists develop new and better ways to diagnose and treat children affected by rare and complex medical disorders.

Paulette McRae, PhD, Associate Director of Specialty Programs and Diversity in the Office of Academic Training and Outreach Programs, has devoted her career to Diversity, Equity, and Inclusion initiatives that open doors for the next generation, so that they can see how they can make a difference in research.

Seeing discoveries happen is "one of the most invigorating and exciting parts of my job," shares Bench to Bedside guest, Madeline Bell, Children's Hospital of Philadelphia President and Chief Executive Officer. Hear how research touches every part of CHOP, and the ways we're continuing our legacy of 100 years of trailblazing research.

We’re celebrating the 100th anniversary of the first research lab at Children’s Hospital of Philadelphia! Our Bench to Bedside guest hasn’t been a CHOP employee for quite *that* long, but he has dedicated three-and-a-half decades of his career here. Meet Howard Eck, director of Research Resources, who knows every corner of the Research Institute and sets our scientists’ laboratories up for success.