Brainforest Café

As the psychedelic renaissance surges, wild sources are collapsing under demand—peyote takes decades to grow, safrole extraction is destroying Southeast Asian forests, and Sonoran Desert toads are being overharvested. In his book Bioengineering Enlightenment, Prof. Jeffrey Gerst proposes a radical solution: engineer yeast or fast-growing plants to produce psychedelic compounds sustainably. But at what cost? Dennis McKenna warns this could strip these substances from their cultural and ecological roots, veering into biopiracy. Together, they debate biotech vs. tradition, exploring alternatives like community-led agroforestry, symbiotic rights, and the “Om Fund” to return profits to Indigenous stewards. They also revisit Terence McKenna’s “Stoned Ape” hypothesis, asking whether paleogenomics could experimentally probe the evolution of human consciousness. - - - Jeffrey Gerst, born and raised in New York, is a Professor of Biology with over three decades of academic experience. He began his career at the Mount Sinai School of Medicine and has since held a long-standing position at the Weizmann Institute of Science in Israel, where he serves as the Besen-Brender Chair of Microbiology and Parasitology. His research focuses on how proteins are correctly localized within cells, particularly through the trafficking of messenger RNA (mRNA), a process essential for normal cellular function and disease prevention. Among his key contributions, Gerst’s work has demonstrated that mammalian cells can transfer mRNA between one another, revealing a novel form of intercellular communication. His lab is now exploring this mechanism as a potential gene therapy approach to treat rare genetic disorders such as Tay-Sachs, cystic fibrosis, and Gaucher’s disease by enabling targeted RNA delivery within the body. In addition to his biomedical research, Gerst advocates for the sustainable production of psychedelic compounds using genetic engineering. He is the author of Bioengineering Enlightenment and has presented this work at major scientific conferences. Learn more about your ad choices. Visit megaphone.fm/adchoices

Nissan started his career as a medical doctor and began his work as a general practitioner in an urban community clinic system. He then specialized in ophthalmology and practiced in a small town for 36 years. He became dissatisfied working strictly on the physical level and received training in Gestalt psychotherapy and had a small private practice. He became interested in the field of Natural Vision Improvement which combined his interest in vision with present moment, embodied presence. A reading from a tarot card reading psychic suggested the need for working in and with the spiritual realm to facilitate the Natural Vision work and suggested there were some gifts for him in shamanism. His wife had had a powerful experience in a ceremony with Don José Campos and encouraged him to explore Ayahuasca as a method to open himself spiritually. He had two very different , but powerful experiences with Don José and participated in a plant dieta in the Amazon in 2005 with Don José. He received what he interpreted as an initiatory experience and felt called to be trained as a vegetalista. He embarked on the training under Don José and Don Lucho’s guidance and began leading ceremonies in the US in 2009 and in 2011 began leading plant dietas in the Amazon. He continues to lead ceremonies in various locations in the US and occasionally Canada and leads dietas in the Amazon twice a year. Learn more about your ad choices. Visit megaphone.fm/adchoices

Kevin Reed, founder and president of the Entheogen Stewardship Project, a vital new nonprofit organization dedicated to protecting culturally significant plant and animal species sacred to indigenous communities worldwide.Kevin brings a remarkable 45-year journey as a student of psychedelic science and culture to this crucial conservation work. His path began in 1984 under the mentorship of legendary researchers Sasha and Anne Shulgin, followed by profound connections with iconic figures including Wavy Gravy, Jack Herer, Timothy Leary, Rick Strassman, and many others who have shaped the modern psychedelic renaissance.Kevin's hands-on expertise spans an impressive range of fields: from teaching cannabis extraction in the mountains of Jamaica in 1985, to large-scale indoor cultivation in the Netherlands, to designing and successfully opening a state-of-the-art Type 7 cannabis manufacturing facility in California. His diverse interests encompass mycology, conservation biology, indigenous traditions, accelerated learning, transpersonal psychology, and ethical wildcrafting—principles that now support his conservation philosophy.The Entheogen Stewardship Project represents the culmination of Kevin's decades-long commitment to both psychedelic wisdom, indigenous rights and environmental protection. The organization combats illegal trafficking and exploitation of endangered entheogenic species while fostering respectful collaboration with all indigenous communities whose ancestral knowledge have safeguarded these sacred plant and animal spirits for millennia.Kevin's work addresses one of the most pressing issues facing our community today: how do we honor and protect the plant and animal teachers that have guided human consciousness for thousands of years, while ensuring their survival for future generations? Learn more about your ad choices. Visit megaphone.fm/adchoices

Tony Ācworth (pronounced Ayk-worth) is a visionary herbalist, psychedelic advocate, forest guide, and self-described “wily wizard” living with his wife and five-year-old son amid the coastal rainforests of Brentwood Bay, Vancouver Island. For 15 plus years, Tony has walked the plant (and mushroom) path, logged over 5,000 clinical hours doing comprehensive intakes with patients, helping them untangle what truly plagues the mind, body, and spirit. Under the mentorship of herbal elder and prolific author and mycologist Robert Rogers, Tony deepened his reverence for the fungal world and its wisdom. In 2015, he was hired to work in Pacific Rim College’s herbal dispensary. Soon after he created and began teaching their first medicinal mushroom materia medica. From here, Tony began offering herbal clinics, nutrition courses, herbal therapeutics and mycological exploration weekends for students in the community herbalist, nutrition, and permaculture programs at the College. At home, he spent a decade developing his own ritual for psilocybin ceremonies, immersing himself in shamanism from Iquitos to the moss-laden forests of Vancouver Island.This led to guiding individuals and men’s groups through the ritual experience, facilitating deeppersonal explorations for those who participated. Tony is also the creator behind DelOs, his heart-led line of herbal-supported mushroom microdose blends, with the expressed purpose of supporting the human body and nervous system with herbal medicine to help rewire stagnant, disserving patterns and improve overall well-being. In 2026, he will expand his offerings by launching a dedicated Psychedelic Therapy Training Program at Pacific Rim College, further bridging ancestral plant wisdom with modern integration practice.Recently, Tony blends mushroom intelligence with machines as a mycelial-minded systems tinkerer building ethical, living AI ecosystems designed to help people recalibrate and remember who they truly are. His work guides both personal recalibration and scalable AI solutions for human-centered collaboration, ensuring that advanced technology uplifts humanity. He’s a father, a leatherworker, a Raspberry Pi hobbyist and if he appears in your life, chances are, the mushrooms arranged it. Tony Ācworth is a techno-mystic wizard: part forest guide, part quantum gardener, part mycelial ambassador – all heart. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Andrew Gallimore is a computational neurobiologist, chemical pharmacologist, and writer, living and working in Tokyo. He has a master’s degree in chemical pharmacology and a PhD in biological chemistry from the University of Cambridge and has held postdoctoral research fellowships in computational neuroscience at the Universities of York, Oxford, and Okinawa. He has been fascinated by the neuropharmacology of psychedelics for more than two decades and is the author of three books: Alien Information Theory -- Psychedelic Drug Technologies and the Cosmic Game; Reality Switch Technologies -- Psychedelics as Tools for the Discovery and Exploration of New Worlds.; and the forthcoming Death by Astonishment -- Confronting the Mystery of the World’s Strangest Drug, which focuses on the history of DMT and science’s continuing struggle to understand how such a simple naturally-occurring molecule can have such astonishing effects on the human mind. His current interests lie in implications of DMT in understanding the nature of reality, and how it might be developed as a tool for extended communication with non-human intelligences inaccessible to normal waking consciousness. Learn more about your ad choices. Visit megaphone.fm/adchoices

Paul Stamets, speaker, author, mycologist, medical researcher and entrepreneur, is considered an intellectual and industry leader in fungi: habitat, medicinal use, and production. He lectures extensively to deepen the understanding and respect for the organisms that literally exist under every footstep taken on this path of life. His presentations cover a range of mushroom species and research showing how mushrooms can help the health of people and planet. His central premise is that habitats have immune systems, just like people, and mushrooms are cellular bridges between the two. Our close evolutionary relationship to fungi can be the basis for novel pairings in the microbiome that lead to greater sustainability and immune enhancement. Paul’s philosophy is that “MycoDiversity is BioSecurity.” He sees the ancient Old Growth forests of the Pacific Northwest as a resource of incalculable value, especially in terms of its fungal genome. A dedicated hiker and explorer, his passion is to preserve and protect as many ancestral strains of mushrooms as possible from these pristine woodlands. His research is considered breakthrough by thought leaders for creating a paradigm shift for helping ecosystems survive worldwide.Paul´s most recent book (2025) is called "Psilocybin Mushrooms in Their Natural Habitats".oms in Their Natural Hbin Mushrooms in Their Natural Habitats Learn more about your ad choices. Visit megaphone.fm/adchoices