Applying real world evidence to clinical trials with Cristina Chang
From Clinical Data Talks by CRScube
June 4, 2025 · 27 min · Episode 6
About this episode
Dr. Cristina Chang discusses the importance of real-world evidence in clinical trials and its impact on patient outcomes and regulatory processes.
Applying real world evidence to clinical trials with Cristina Chang In the final episode of season 1, Sylvain Berthelot welcomes Dr. Cristina Chang, Chief Medical Officer at HiRO, to unpack the growing importance of real-world evidence (RWE) in clinical development. With decades of experience across global pharmaceutical companies, Cristina shares her deep insights into how real-world data is being applied to clinical trials to enhance patient outcomes, regulatory submissions, and post-marketing strategies. She discusses the practical considerations for using RWE, from data collection challenges to ensuring scientific rigor, as well as how the regulatory landscape is evolving to support these efforts. Cristina also reflects on cultural and organizational changes needed to integrate RWE into clinical development successfully, and how emerging technologies and cross-functional collaboration can drive this transformation. Join us as we explore how real-world evidence is shifting from a buzzword to a critical component of evidence generation in modern clinical research.
People in this episode
Host: Sylvain Berthelot
Guest: Cristina Chang
Topics covered
- real world evidence
- clinical trials
- patient outcomes
- regulatory submissions
- post-marketing strategies
- data collection
- scientific rigor
- regulatory landscape
- cultural changes
- organizational changes
- emerging technologies
- cross-functional collaboration
Keywords
- clinical development
- evidence generation
- modern clinical research
Mentioned in this episode
Products: real-world data
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