LayerZero CEO Brian Pellegrino on Interoperability, Stablecoins, and Bringing TradFi On-Chain

LayerZero CEO Brian Pellegrino on Interoperability, Stablecoins, and Bringing TradFi On-Chain

From Crypto In America by Crypto In America

April 1, 2026 · 53 min

About this episode

Bryan Pellegrino discusses the evolution of crypto, interoperability, and the connection between traditional finance and blockchain.

Bryan Pellegrino is the Co-Founder & CEO of LayerZero Labs. In this conversation, we discuss how a 2011 U.S. online poker ban led him to crypto as an “escape hatch,” early sports gambling, learning how insecure and centralized cross-chain bridges were, interoperability, the 700% increase in traffic on LayerZero, building an L1, and working with institutions to connect tradfi to blockchains. This episode is sponsored by Gemini: https://gemini.com/CIA Watch On YouTube: https://youtu.be/j1qHWn-a6SU Watch On Rumble: https://rumble.com/v77wham-layerzero-ceo-brian-pellegrino-on-interoperability-stablecoins-and-bringing.html Please note that this podcast is for informational purposes only and any views shared by anyone on the show are opinions, not financial advice. The host or guests may have a direct or indirect financial interest in content mentioned in this episode. This show is powered by Sei. Learn more about Sei: https://www.sei.io/ Follow Crypto in America: https://x.com/CryptoAmerica_ Follow Sei: https://x.com/SeiNetwork Follow our hosts Jacquelyn: https://x.com/jacqmelinek Gerald: https://x.com/thatgerald Eleanor: https://x.com/EleanorTerrett TIMESTAMPS: 0:00 - Welcome…

People in this episode

Hosts: Jacquelyn, Gerald, Eleanor

Guest: Bryan Pellegrino

Topics covered

  • interoperability
  • stablecoins
  • TradFi
  • cross-chain bridges
  • crypto history
  • sports gambling

Keywords

  • LayerZero
  • crypto
  • interoperability
  • stablecoins
  • TradFi
  • cross-chain bridges
  • sports gambling
  • online poker ban

Sponsors

Gemini

Mentioned in this episode

Organizations: LayerZero Labs, Sei

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