33. Do perioperative gabapentinoids decrease postoperative pain?

About this episode

This episode reviews the evidence surrounding the use of gabapentinoids in the perioperative setting and discusses related concepts.

It's our first solo episode! We review the evidence around perioperative use of gabapentinoids (gabapentin and pregabalin) and discuss interesting concepts including trial sequential analysis and minimally important difference. If you enjoy our content, leave a 5-star review on Apple Podcasts and share our content with your colleagues. — Follow us on Instagram @DepthofAnesthesia and on Twitter @DepthAnesthesia for podcast and literature updates. Email us at depthofanesthesia@gmail.com with episode ideas or if you'd like to join our team. Music by Stephen Campbell, MD. — References Dirks J, Fredensborg BB, Christensen D, Fomsgaard JS, Flyger H, Dahl JB. A randomized study of the effects of single-dose gabapentin versus placebo on postoperative pain and morphine consumption after mastectomy. Anesthesiology. 2002 Sep;97(3):560-4. doi: 10.1097/00000542-200209000-00007. PMID: 12218520. Ian Gilron; Is Gabapentin a "Broad-spectrum" Analgesic?. Anesthesiology 2002; 97:537–539 doi: https://doi.org/10.1097/00000542-200209000-00004 Mishriky BM, Waldron NH, Habib AS. Impact of pregabalin on acute and persistent postoperative pain: a systematic review and meta-analysis. Br J Anaesth. 2015…

People in this episode

Host: David Hao, MD

Topics covered

• gabapentinoids
• postoperative pain
• perioperative care
• pain management
• evidence review

Keywords

• gabapentin
• pregabalin
• postoperative pain
• trial sequential analysis
• minimally important difference

Mentioned in this episode

Organizations: Depth of Anesthesia

Books & works: Anesthesiology, Br J Anaesth

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