DÉJÀ VU: LPS and Neonatal Sugars (April 2026 AJP)

About this episode

The episode discusses new data on antenatal corticosteroids and their impact on neonatal hypoglycemia in the late preterm interval.

Yes we have covered antenatal corticosteroids in the late preterm interval on several episodes in the past- it's DEJA VU! However, there is new data in the American Journal of Perinatology (April 2026 ) that is helpful for us as clinicians as we do “shared decision making” with patients in offering betamethasone in the late preterm interval. Listen in for details. 1. Zigron R, Rotem R, Erlichman I, Rottenstreich M, Rosenbloom JI, Porat S, Rottenstreich A. Factors associated with the development of neonatal hypoglycemia after antenatal corticosteroid administration: It's all about timing. Int J Gynaecol Obstet. 2022 Aug;158(2):385-389. doi: 10.1002/ijgo.13975. Epub 2021 Oct 30. PMID: 34625970. 2. Asirwatham A, Loke R, Rose S, Ho J, Leung K, Leftwich HK. Neonatal Hypoglycemia after Antenatal Late Preterm Steroids. Am J Perinatol. 2026 Apr;43(5):616-620. doi: 10.1055/a-2663-5798. Epub 2025 Aug 4. PMID: 40759170. 3. ALPS Trial. NEJM. Published April 7, 2016;374:1311-1320

People in this episode

Host: Hector Chapa

Topics covered

• antenatal corticosteroids
• neonatal hypoglycemia
• shared decision making
• late preterm interval
• clinical data

Keywords

• antenatal corticosteroids
• neonatal hypoglycemia
• betamethasone
• late preterm
• shared decision making
• clinical guidelines

Mentioned in this episode

Organizations: American Journal of Perinatology

Books & works: Int J Gynaecol Obstet, Am J Perinatol, NEJM

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